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Merck

PRKCB

protein kinase C, beta

동의어:
PKC-beta, PKCB, PRKCB1, PRKCB2
:
UniProtKB ID:
Clone ID:
  • Human(5579) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(18751) protein kinase C, beta
  • Rat(25023) protein kinase C, beta
  • Domestic Rabbit(100037719) protein kinase C, beta
  • sheep(101118410) protein kinase C, beta
  • naked mole-rat(101722702) protein kinase C, beta
  • domestic cat(101088970) protein kinase C, beta
  • chicken(416567) protein kinase C, beta
  • dog(489968) protein kinase C, beta
  • cow(282325) protein kinase C, beta

Custom & Knockdown Gene Products

Small Molecule - Agonist

제품 번호
설명
Oleic acid, ≥99% (GC),
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-PKCβ Antibody, clone 2E13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
human, monkey, mouse
응용분야
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-p-PKCβ (Ser660) Antibody, clone 2C11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
bovine, human, monkey, mouse, rabbit, rat
응용분야
affinity binding assay
immunocytochemistry

inhibition assay

western blot
Anti-PRKCB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
종별 반응성
human
응용분야
immunofluorescence
Anti-PRKCB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry
Anti-Phospho-PKCalpha/beta II-T638/641 antibody produced in rabbit, ,
종별 반응성
human
응용분야
western blot

Small Molecule - Inhibitor

제품 번호
설명
Hispidin, solid, ≥98% (HPLC),
human
H-7 dihydrochloride, ≥98% (HPLC),
human
Tamoxifen citrate salt, ≥99%,
human
Oleic acid, ≥99% (GC),
human
UCN-01, ≥97% (HPLC), powder,
human

Proteins

제품 번호
설명
Protein kinase CβII isozyme human, >85% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Prkcb,
mouse
MISSION® esiRNA, targeting human PRKCB,
human