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Merck

PIK3CA

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

동의어:
CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha
:
UniProtKB ID:
Clone ID:
  • Human(5290) Summary: Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. [provided by RefSeq, Jul 2008]
  • Mouse(18706) phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
  • Rat(170911) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
  • sheep(101110015) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
  • chicken(424971) phosphoinositide-3-kinase, catalytic, alpha polypeptide
  • dog(488084) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
  • domestic guinea pig(100735084) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
  • naked mole-rat(101711934) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
  • domestic cat(101097413) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
  • cow(282306) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-PI-3 kinase p110α Antibody, clone 1J4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
human, monkey
응용분야
affinity binding assay
flow cytometry

immunohistochemistry

western blot
Anti-PIK3CA antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
immunohistochemistry
western blot
Monoclonal Anti-PIK3CA antibody produced in mouse, clone 3G3, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
proximity ligation assay
Anti-PIK3CA antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-PIK3CA antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL8345, purified immunoglobulin, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
western blot

Small Molecule - Inhibitor

제품 번호
설명
PF-04691502, ≥98% (HPLC),
human

Proteins

제품 번호
설명
PI3 kinase (p110a/p85a) Active human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
human
PI3K (p110-α/p85-α), active, His tagged from mouse and human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
mouse
PI3 Kinase (p110α/p85α) Protein, active, 20 µg, Active complex of N-terminal His6-tagged recombinant full-length human p110α & untagged, recombinant, full length, human p85α. For use in Kinase Assays.,
human
PI3 kinase [p110a(H1047R)/p85a] Active human, recombinant, expressed in baculovirus infected insect cells, ≥60% (SDS-PAGE),
human
PI3 kinase [p110a(E545K)/p85a] Active human, recombinant, expressed in baculovirus infected insect cells, ≥55% (SDS-PAGE),
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human PIK3CA (2),
human
MISSION® esiRNA, targeting human PIK3CA,
human
MISSION® esiRNA, targeting mouse Pik3ca,
mouse