콘텐츠로 건너뛰기
Merck

PDE4C

phosphodiesterase 4C, cAMP-specific

동의어:
DPDE1
:
UniProtKB ID:
Clone ID:
  • Human(5143) Summary: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
  • Mouse(110385) phosphodiesterase 4C, cAMP specific
  • Rat(290646) phosphodiesterase 4C, cAMP-specific
  • dog(609938) phosphodiesterase 4C, cAMP-specific
  • cow(524624) phosphodiesterase 4C, cAMP-specific
  • domestic cat(101086123) phosphodiesterase 4C, cAMP-specific
  • naked mole-rat(101703048) phosphodiesterase 4C, cAMP-specific
  • sheep(101111282) phosphodiesterase 4C, cAMP-specific

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Antagonist

제품 번호
설명
Theophylline, Pharmaceutical Secondary Standard; Certified Reference Material,
human
Theophylline, European Pharmacopoeia (EP) Reference Standard,
human
Theophylline, United States Pharmacopeia (USP) Reference Standard,
human
Theophylline melting point standard, United States Pharmacopeia (USP) Reference Standard,
human
Theophylline, phyproof® Reference Substance,
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Monoclonal Anti-PDE4C antibody produced in mouse, clone 6A10, ascites fluid,
종별 반응성
human
응용분야
ELISA
western blot
Monoclonal Anti-PDE4C, (N-terminal) antibody produced in mouse, clone 4E5, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
immunofluorescence

western blot
Anti-PDE4C antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
Anti-PDE4C antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry

Small Molecule - Inhibitor

제품 번호
설명
Ibudilast, ≥99% (HPLC), solid,
human
Amlexanox, ≥98% (HPLC),
human
Roflumilast, ≥98% (HPLC),
human
7-(2,3-Dihydroxypropyl)theophylline, ,
human
Diprophylline, European Pharmacopoeia (EP) Reference Standard,
human

Proteins

제품 번호
설명
PDE4C Active from mouse, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
mouse
PDE4C1 Active human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Pde4c,
mouse
MISSION® esiRNA, targeting human PDE4C,
human