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Merck

PAK3

p21 protein (Cdc42/Rac)-activated kinase 3

동의어:
CDKN1A, MRX30, MRX47, OPHN3, PAK3beta, bPAK, hPAK3
:
UniProtKB ID:
Clone ID:
  • Human(5063) Summary: PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(18481) p21 protein (Cdc42/Rac)-activated kinase 3
  • Rat(29433) p21 protein (Cdc42/Rac)-activated kinase 3
  • domestic guinea pig(100721049) p21 protein (Cdc42/Rac)-activated kinase 3
  • naked mole-rat(101712811) p21 protein (Cdc42/Rac)-activated kinase 3
  • fruit fly(41995) CG14895 gene product from transcript CG14895-RD
  • chicken(422342) p21 protein (Cdc42/Rac)-activated kinase 3
  • Domestic Rabbit(100347273) p21 protein (Cdc42/Rac)-activated kinase 3
  • dog(492067) p21 protein (Cdc42/Rac)-activated kinase 3
  • domestic cat(101092248) p21 protein (Cdc42/Rac)-activated kinase 3
  • Horse(100054315) p21 protein (Cdc42/Rac)-activated kinase 3
  • cow(534526) p21 protein (Cdc42/Rac)-activated kinase 3
  • sheep(101110391) p21 protein (Cdc42/Rac)-activated kinase 3

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Monoclonal Anti-PAK3 antibody produced in mouse, clone 3A12, purified immunoglobulin, buffered aqueous solution,
종별 반응성
mouse
응용분야
ELISA
immunofluorescence

western blot
Anti-PAK3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
western blot
Anti-phospho PIX Antibody (Ser340), from rabbit, purified by affinity chromatography,
종별 반응성
human, mouse, rat
응용분야
western blot
Anti-phospho-PAK3 (pSer154) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunohistochemistry

western blot
Anti-PAK3 antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
immunohistochemistry
western blot

Proteins

제품 번호
설명
PAK3, active, GST tagged from mouse, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
mouse

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human PAK3,
human