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Merck

MAP2K6

mitogen-activated protein kinase kinase 6

동의어:
MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3
:
UniProtKB ID:
Clone ID:
  • Human(5608) Summary: This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq, Jul 2008]
  • Mouse(26399) mitogen-activated protein kinase kinase 6
  • Rat(114495) mitogen-activated protein kinase kinase 6
  • dog(480454) mitogen-activated protein kinase kinase 6
  • chicken(417445) mitogen-activated protein kinase kinase 6
  • Zebrafish(65239) mitogen-activated protein kinase kinase 6
  • domestic guinea pig(100731419) mitogen-activated protein kinase kinase 6
  • naked mole-rat(101703028) mitogen-activated protein kinase kinase 6
  • sheep(101115047) mitogen-activated protein kinase kinase 6
  • Domestic Rabbit(100355230) mitogen-activated protein kinase kinase 6
  • cow(286883) mitogen-activated protein kinase kinase 6
  • domestic cat(101089813) mitogen-activated protein kinase kinase 6
  • Horse(100053056) mitogen-activated protein kinase kinase 6

Custom & Knockdown Gene Products

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-MAP2K6 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
western blot
Anti-MKK6 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunohistochemistry

western blot
Anti-MAP2K6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human, mouse, rat
응용분야
immunofluorescence
immunohistochemistry

western blot
SAPK Pathway Explorer Antibody Minipack, Upstate®,
종별 반응성
응용분야
Monoclonal Anti-MAP2K6 antibody produced in mouse, clone 2F2, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
immunofluorescence

proximity ligation assay

western blot

Small Molecule - Inhibitor

제품 번호
설명
PD 98,059, solid,
human

Proteins

제품 번호
설명
MKK6/SKK3, active human, ≥80% (SDS-PAGE), recombinant, expressed in E. coli, Maltose binding protein tagged, buffered aqueous solution,
human
MKK6/SKK3 Protein, inactive, 50 g, Unactive, recombinant human MKK6, amino acids 4-end, fused at the N-terminus to a Mal-E tag, for use in Kinase Assays.,
human
MKK6 active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE),
human
MKK6/SKK3 Protein, active, 10 µg, Active, N-terminal, maltose binding protein tagged, human MKK6/SKK3 fusion protein, amino acids 4-end. For use in Kinase Assays.,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human MAP2K6,
human
MISSION® esiRNA, targeting mouse Map2k6,
mouse