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Merck

LMNA

lamin A/C

동의어:
CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, LMNL1, PRO1
:
UniProtKB ID:
Clone ID:
  • Human(4000) Summary: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012]
  • Mouse(16905) lamin A
  • Rat(60374) lamin A/C
  • domestic guinea pig(100735212) lamin A/C
  • chicken(415464) lamin A/C
  • sheep(101107924) lamin A/C
  • cow(404144) lamin A/C
  • domestic cat(101086199) lamin A/C
  • Horse(100057663) lamin A/C
  • dog(480124) lamin A/C
  • Zebrafish(195815) lamin A
  • naked mole-rat(101704567) lamin A/C

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-Progerin antibody, Mouse monoclonal, clone 13A4, purified from hybridoma cell culture,
종별 반응성
human
응용분야
immunofluorescence
immunoprecipitation (IP)

western blot
Anti-phospho-Lamin A/C (pSer392) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Lamin A, mature antibody, Mouse monoclonal, clone 4A4, purified from hybridoma cell culture,
종별 반응성
human
응용분야
immunofluorescence
western blot
Anti-Lamin A/C antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti- Lamin A/C antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
immunohistochemistry
western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human LMNA,
human
MISSION® esiRNA, targeting mouse Lmna,
mouse