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Merck

LEF1

lymphoid enhancer-binding factor 1

동의어:
LEF-1, TCF10, TCF1ALPHA, TCF7L3
:
UniProtKB ID:
Clone ID:
  • Human(51176) Summary: This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
  • Mouse(16842) lymphoid enhancer binding factor 1
  • Rat(161452) lymphoid enhancer binding factor 1
  • domestic guinea pig(100716066) lymphoid enhancer-binding factor 1
  • naked mole-rat(101711023) lymphoid enhancer-binding factor 1
  • dog(478507) lymphoid enhancer-binding factor 1
  • Zebrafish(30701) lymphocyte enhancer binding factor 1
  • domestic cat(101088077) lymphoid enhancer-binding factor 1
  • cow(535399) lymphoid enhancer-binding factor 1
  • chicken(395865) lymphoid enhancer-binding factor 1

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-LEF1 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
종별 반응성
bovine, dog, goat, guinea pig, horse, human, mouse, rabbit, rat
응용분야
immunohistochemistry
western blot
Anti-phospho-LEF-1 (pSer42) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
western blot
Anti-LEF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-LEF-1 (β-Catenin binding domain) antibody produced in mouse, clone REMB1, ~1 mg/mL, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
western blot
Monoclonal Anti-LEF-1 (HMG DNA Binding Domain) antibody produced in mouse, ~1 mg/mL, clone REMB6, purified immunoglobulin,
종별 반응성
human
응용분야
western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human LEF1,
human