콘텐츠로 건너뛰기
Merck

KCNQ4

potassium voltage-gated channel, KQT-like subfamily, member 4

동의어:
DFNA2, DFNA2A, KV7.4
:
UniProtKB ID:
Clone ID:
  • Human(9132) Summary: The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(60613) potassium voltage-gated channel, subfamily Q, member 4
  • Rat(298496) potassium voltage-gated channel, KQT-like subfamily, member 4
  • chicken(419643) potassium voltage-gated channel, KQT-like subfamily, member 4
  • naked mole-rat(101714294) potassium voltage-gated channel, KQT-like subfamily, member 4
  • domestic guinea pig(100716024) potassium voltage-gated channel, KQT-like subfamily, member 4
  • sheep(101122655) potassium voltage-gated channel, KQT-like subfamily, member 4
  • Domestic Rabbit(100358271) potassium voltage-gated channel, KQT-like subfamily, member 4
  • domestic cat(101091641) potassium voltage-gated channel, KQT-like subfamily, member 4
  • Horse(100067963) potassium voltage-gated channel, KQT-like subfamily, member 4
  • cow(528741) potassium voltage-gated channel, KQT-like subfamily, member 4
  • dog(482451) potassium voltage-gated channel, KQT-like subfamily, member 4

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Activator

제품 번호
설명
BMS 204352, ≥98% (HPLC),
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-KCNQ4 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
western blot
Monoclonal Anti-KCNQ4 antibody produced in mouse, clone 2H6, purified immunoglobulin, buffered aqueous solution,
종별 반응성
mouse
응용분야
ELISA
western blot

Small Molecule - Blocker

제품 번호
설명
Guanidine hydrochloride solution, BioUltra, ~8 M in H2O,
human
Guanidine hydrochloride solution, Colorless liquid, 7.8 - 8.3 M, pH- 4.5 - 5.5,
human
3,4-Diaminopyridine, ≥98%,
human
Guanidine hydrochloride, ≥99.0% (AT),
human
Guanidine hydrochloride, ≥98%,
human

Small Molecule - Inhibitor

제품 번호
설명
N-Ethylmaleimide, crystalline, ≥98% (HPLC),
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Kcnq4,
mouse
MISSION® esiRNA, targeting human KCNQ4,
human