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Merck

HTR1B

5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled

동의어:
5-HT1B, 5-HT1DB, HTR1D2, HTR1DB, S12
:
UniProtKB ID:
Clone ID:
  • Human(3351) Summary: The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]
  • Mouse(15551) 5-hydroxytryptamine (serotonin) receptor 1B
  • Rat(25075) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • chicken(421858) 5-hydroxytryptamine (serotonin) receptor 1B
  • Zebrafish(561647) 5-hydroxytryptamine (serotonin) receptor 1B
  • dog(403741) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • cow(317707) 5-hydroxytryptamine (serotonin) receptor 1B
  • Horse(100009680) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • domestic cat(100144391) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • Domestic Rabbit(100009594) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • sheep(101111375) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • domestic guinea pig(100135543) 5-hydroxytryptamine (serotonin) receptor 1B

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Small Molecule - Agonist

제품 번호
설명
Naratriptan hydrochloride, ≥98% (HPLC),
human
Sumatriptan for system suitability, European Pharmacopoeia (EP) Reference Standard,
human
Naratriptan hydrochloride, United States Pharmacopeia (USP) Reference Standard,
human
Sumatriptan succinate, ≥98% (HPLC), solid,
human
Rizatriptan benzoate salt, ≥98% (HPLC),
human

Small Molecule - Allosteric Modulator

제품 번호
설명
DCEBIO, ≥98% (HPLC), solid,
human

Small Molecule - Antagonist

제품 번호
설명
GR 127935 hydrochloride hydrate, >98% (HPLC), powder,
human
Methiothepin mesylate salt, ≥98% (HPLC), solid,
human
(S)-(−)-Propranolol hydrochloride, ≥98% (TLC), powder,
human
Trazodone hydrochloride, ≥99% (HPLC), powder,
human
Methysergide maleate salt, solid,
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-HTR1B antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunofluorescence

western blot
Anti-5-HT-1B antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunofluorescence

immunohistochemistry
Anti-Serotonin Receptor 1B/HTR1B antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
canine, human, mouse, rat
응용분야
ELISA
western blot

Small Molecule - Blocker

제품 번호
설명
(S)-(−)-Propranolol hydrochloride, ≥98% (TLC), powder,
human
Trazodone hydrochloride, ≥99% (HPLC), powder,
human
Trimipramine maleate salt, ≥98% (TLC), powder,
human
Zimelidine dihydrochloride, solid,
human

Small Molecule - Inhibitor

제품 번호
설명
Trazodone hydrochloride, ≥99% (HPLC), powder,
human
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
human
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
human
Fluvoxamine maleate, solid,
human
Sertraline hydrochloride, ≥98% (HPLC),
human

Small Molecule - Ligand

제품 번호
설명
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
human

Small Molecule - Metabolite

제품 번호
설명
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
human

Small Molecule - Precursor

제품 번호
설명
5-Hydroxy-L-tryptophan, powder,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Htr1b,
mouse