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Merck

GABRD

gamma-aminobutyric acid (GABA) A receptor, delta

동의어:
EIG10, EJM7, GEFSP5
:
UniProtKB ID:
Clone ID:
  • Human(2563) Summary: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(14403) gamma-aminobutyric acid (GABA) A receptor, subunit delta
  • Rat(29689) gamma-aminobutyric acid (GABA) A receptor, delta
  • Zebrafish(571422) gamma-aminobutyric acid (GABA) A receptor, delta
  • chicken(770710) gamma-aminobutyric acid (GABA) A receptor, delta
  • cow(508711) gamma-aminobutyric acid (GABA) A receptor, delta
  • dog(489609) gamma-aminobutyric acid (GABA) A receptor, delta
  • sheep(101122539) gamma-aminobutyric acid (GABA) A receptor, delta
  • domestic cat(101087589) gamma-aminobutyric acid (GABA) A receptor, delta
  • domestic guinea pig(100735228) gamma-aminobutyric acid (GABA) A receptor, delta
  • naked mole-rat(101700143) gamma-aminobutyric acid (GABA) A receptor, delta

Custom & Knockdown Gene Products

Small Molecule - Agonist

제품 번호
설명
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
human

Small Molecule - Allosteric Modulator

제품 번호
설명
Ganaxolone, solid, ≥98% (HPLC),
human, mouse
Isoflurane, ,
human
Halothane, United States Pharmacopeia (USP) Reference Standard,
human
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
human
Acamprosate calcium, British Pharmacopoeia (BP) Reference Standard,
human

Small Molecule - Antagonist

제품 번호
설명
Flumazenil, United States Pharmacopeia (USP) Reference Standard,
human
Ganaxolone, solid, ≥98% (HPLC),
human, mouse
Flumazenil, >99% (HPLC), solid,
rat, human
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
human
Acamprosate calcium, British Pharmacopoeia (BP) Reference Standard,
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-GABRD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-GABRD antibody produced in rabbit, affinity isolated antibody,
종별 반응성
bovine, dog, human, mouse, rabbit
응용분야
immunohistochemistry
western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Gabrd,
mouse
MISSION® esiRNA, targeting human GABRD,
human