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Merck

EIF2S1

eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa

동의어:
EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A
:
UniProtKB ID:
Clone ID:
  • Human(1965) Summary: The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]
  • Mouse(13665) eukaryotic translation initiation factor 2, subunit 1 alpha
  • Rat(54318) eukaryotic translation initiation factor 2, subunit 1 alpha
  • chicken(423279) eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
  • Goat(100861133) eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
  • domestic cat(101091455) eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
  • sheep(101113414) eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
  • domestic guinea pig(100716377) eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
  • cow(327694) eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
  • dog(480361) eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
  • naked mole-rat(101723170) eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-phospho-EIF2S1 (pSer49) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
immunofluorescence
immunohistochemistry

western blot
Anti-phospho-EIF2S1 (pSer51) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
immunofluorescence
immunohistochemistry

western blot
Anti-EIF2S1, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
bovine, dog, goat, guinea pig, horse, human, mouse, rabbit, rat
응용분야
western blot
Monoclonal Anti-EIF2S1 (phospho S51) antibody produced in rabbit, clone IO-5,
종별 반응성
human
응용분야
flow cytometry
immunofluorescence

immunohistochemistry

western blot
Anti-eIF-2α Antibody, clone 3M6 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
human
응용분야
affinity binding assay
flow cytometry

immunocytochemistry

western blot

Proteins

제품 번호
설명
EIF2S1, His tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Eif2s1,
mouse
MISSION® esiRNA, targeting human EIF2S1,
human