BACE1
beta-site APP-cleaving enzyme 1
๋์์ด:
ASP2, BACE, HSPC104
์ข
:
Human BACE1 (23621), Mouse Bace1 (23821), Rat Bace1 (29392), Horse BACE1 (100071137), naked mole-rat Bace1 (101701890), sheep BACE1 (101119667), dog BACE1 (489390), cow BACE1 (614333), chicken BACE1 (419768), Zebrafish bace1 (403005) ...๋
UniProtKB ID:
Clone ID:
- Human(23621) Summary: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
- Mouse(23821) beta-site APP cleaving enzyme 1
- Rat(29392) beta-site APP cleaving enzyme 1
- Horse(100071137) beta-site APP-cleaving enzyme 1
- naked mole-rat(101701890) beta-site APP-cleaving enzyme 1
- sheep(101119667) beta-site APP-cleaving enzyme 1
- dog(489390) beta-site APP-cleaving enzyme 1
- cow(614333) beta-site APP-cleaving enzyme 1
- chicken(419768) beta-site APP-cleaving enzyme 1
- Zebrafish(403005) beta-site APP-cleaving enzyme 1
- domestic cat(101086840) beta-site APP-cleaving enzyme 1
- domestic guinea pig(100135485) beta-site APP cleaving enzyme 1
- Domestic Rabbit(100343442) beta-site APP-cleaving enzyme 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Activity Assay
์ ํ ๋ฒํธ
์ค๋ช
์ข
ฮฒ-Secretase (BACE1) Activity Detection Kit (Fluorescent), 1 kit sufficient for 250 reactions,
์ข
human
Antibodies
์ ํ ๋ฒํธ
์ค๋ช
์ข
๋ณ ๋ฐ์์ฑ
์์ฉ๋ถ์ผ
Anti-BACE1 antibody produced in rabbit, affinity isolated antibody,
์ข
๋ณ ๋ฐ์์ฑ
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
์์ฉ๋ถ์ผ
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-BACE Antibody, CT, Chemiconยฎ, from rabbit,
์ข
๋ณ ๋ฐ์์ฑ
human
์์ฉ๋ถ์ผ
immunohistochemistry
western blot
western blot
Anti-BACE Antibody, CT, clone 61-3E7, clone 61-3E7, Chemiconยฎ, from mouse,
์ข
๋ณ ๋ฐ์์ฑ
human, mouse, primate, rat
์์ฉ๋ถ์ผ
immunoprecipitation (IP)
western blot
western blot
Anti-BACE1 Antibody, clone 7C5T7, Rabbit Monoclonal, ,
์ข
๋ณ ๋ฐ์์ฑ
human, rat
์์ฉ๋ถ์ผ
western blot
Anti-BACE antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
์ข
๋ณ ๋ฐ์์ฑ
human, mouse
์์ฉ๋ถ์ผ
ELISA
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
Small Molecule - Inhibitor
Kits
์ ํ ๋ฒํธ
์ค๋ช
์ข
ฮฒ-Secretase (BACE1) Activity Detection Kit (Fluorescent), 1 kit sufficient for 250 reactions,
์ข
human
Proteins
์ ํ ๋ฒํธ
์ค๋ช
์ข
ฮฒ-Secretase human, recombinant, expressed in HEK 293 cells (C-terminal FLAG tagged), extracellular domain, โฅ10,000 units/mg protein, โฅ90% (SDS-PAGE), buffered aqueous solution,
์ข
human