AR
androgen receptor
동의어:
AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM
종:
Human AR (367), Mouse Ar (11835), Rat Ar (24208), fruit fly ar (44503), Zebrafish ar (100005148), chicken AR (422165), dog AR (403588), domestic cat AR (101081787), domestic cat AR (751827), Horse AR (100033980) ...더
UniProtKB ID:
Clone ID:
- Human(367) Summary: The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
- Mouse(11835) androgen receptor
- Rat(24208) androgen receptor
- fruit fly(44503) abdomen rotatum
- Zebrafish(100005148) androgen receptor
- chicken(422165) androgen receptor
- dog(403588) androgen receptor
- domestic cat(101081787) androgen receptor
- domestic cat(751827) androgen receptor
- Horse(100033980) androgen receptor
- cow(280675) androgen receptor
- sheep(443042) androgen receptor
- Goat(100860827) androgen receptor
- Domestic Rabbit(100009193) androgen receptor
- domestic guinea pig(100726891) androgen receptor
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Activator
Small Molecule - Agonist
제품 번호
설명
종
Testosterone for system suitability A, CRS, European Pharmacopoeia (EP) Reference Standard,
종
human
Small Molecule - Antagonist
Antibodies
제품 번호
설명
종별 반응성
응용분야
Anti-Androgen Receptor antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Androgen Receptor antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human
응용분야
ChIP
ELISA
immunohistochemistry
western blot
ELISA
immunohistochemistry
western blot
Anti-AR antibody produced in rabbit, affinity isolated antibody,
종별 반응성
dog, horse, human, pig
응용분야
western blot
Anti-AR (n-terminal) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM254, purified immunoglobulin,
종별 반응성
human
응용분야
immunohistochemistry
western blot
western blot
ANTI-ANDROGEN RECEPTOR (ANDR) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human, mouse
응용분야
immunohistochemistry
western blot
western blot
Small Molecule - Blocker
제품 번호
설명
종
Small Molecule - Inhibitor
Small Molecule - Ligand
Proteins
제품 번호
설명
종
Androgen receptor (650-920), human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
종
human