- Platinum complex as a nanomolar protein kinase inhibitor.
Platinum complex as a nanomolar protein kinase inhibitor.
Inorganic chemistry (2007-03-23)
Douglas S Williams, Patrick J Carroll, Eric Meggers
PMID17375909
ABSTRACT
A pyridocarbazole platinum complex, which matches the overall shape of the natural product staurosporine, binds with high affinity at the adenosine triphosphate binding site of glycogen synthase kinase 3 (GSK-3alpha).
MATERIALS