SML2047
BPAM344
≥98% (HPLC)
Synonym(s):
BPAM344, 4-Cyclopropyl-3,4-dihydro-7-fluoro-2H-1,2,4-benzothiadiazine 1,1-dioxide
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About This Item
Empirical Formula (Hill Notation):
C10H11FN2O2S
CAS Number:
Molecular Weight:
242.27
UNSPSC Code:
12352200
NACRES:
NA.77
Assay
≥98% (HPLC)
form
powder
color
white to beige
storage temp.
2-8°C
SMILES string
O=S1(C2=CC(F)=CC=C2N(C3CC3)CN1)=O
Biochem/physiol Actions
BPAM344 is a potent positive allosteric modulator (PAM) on the three KAR subunits GluK1b, GluK2a, and GluK3a. BPAM344 potentiates glutamate-evoked currents of GluK2a 21-fold, and noticeably decreases desensitization kinetics (from 5.5 to 775 ms).
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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