M-005

Morphine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Empirical Formula (Hill Notation): C₁₇H₁₉NO₃
• CAS Number: 57-27-2
• Molecular Weight: 285.34
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• concentration: 1.0 mg/mL in methanol
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): forensics and toxicology
• format: single component solution
• storage temp.: −20°C
• SMILES string: CN1CC[C@]23[C@H]4Oc5c(O)ccc(C[C@@H]1[C@@H]2C=C[C@@H]4O)c35
• InChI: 1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1
• InChI key: BQJCRHHNABKAKU-KBQPJGBKSA-N
• Gene Information: human ... OPRM1(4988)

Description

General description

This certified analytical reference standard is suitable for a variety of GC/MS or LC/MS applications from pain prescription monitoring, clinical toxicology, and urine drug testing to pharmaceutical research and forensic analysis.

Morphine is a natural phenolic alkaloid, commonly used as an analgesic and anti-inflammatory properties. Sold under trade names including MS Contin^®, Kadian^®, Oramorph^®, and Roxanol, morphine is also a commonly abused recreational drug due to its widespread availability and a high potential for addiction.

Application

The certified reference solution (CRM) in solution can also be used as follows:

• Development of a hydrogel-modified carbon paste electrode (HCPE) for the electrochemical determination of morphine in very low volume solutions using differential pulse voltammetry
• Combination of magnetic molecularly imprinted solid phase extraction (MMISPE) with high-performance liquid chromatography (HPLC) to analyze urine samples for quantifying morphine
• Electrochemical detection and measurement of morphine and 3,4-methylenedioxymethamphetamine (MDMA) in human urine and serum samples using carbon nanohorns modified with Pt nanoparticles (CNHs@PtNPs) based sensor
• Simultaneous determination of morphine and naltrexone in bulk and their combined solid dosage formulations using a stability-indicating high-performance liquid chromatographic method combined with a photodiode array detector
• Colorimetric estimation of morphine and ibuprofen in human serum and urine samples as per the difference in the aggregation of citrate-capped gold nanoparticles (AuNPs) analyzed by infra-red (IR) spectroscopy and transmission electron microscopy (TEM)

Features and Benefits

• Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
• Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
• Rigorously tested through real-time stability studies to ensure accuracy and shelf life
• Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
• Flame sealed under argon into ampoules for long-term shelf life
• Offered in a convenient, DEA-exempt format to improve laboratory efficiency

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Kadian is a registered trademark of Actavis Elizabeth LLC

MS Contin is a registered trademark of Purdue Frederick Company

Oramorph is a registered trademark of AAIPharma, Inc.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes,Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup