TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
Synonyms:
EPI, LACI, TFI, TFPI1
Species:
Human TFPI (7035), Mouse Tfpi (21788), Rat Tfpi (29436), cow TFPI (508763), Domestic Rabbit TFPI (100009401), domestic guinea pig Tfpi (100727170), dog TFPI (403921), sheep TFPI (101120391), naked mole-rat Tfpi (101710461), domestic cat TFPI (101098813)
UniProtKB ID:
Gene ID:
- Human(7035) Summary: This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed. [provided by RefSeq, Jul 2008]
- Mouse(21788) tissue factor pathway inhibitor
- Rat(29436) tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
- cow(508763) tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
- Domestic Rabbit(100009401) tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
- domestic guinea pig(100727170) tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
- dog(403921) tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
- sheep(101120391) tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
- naked mole-rat(101710461) tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
- domestic cat(101098813) tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
- chicken(423989) tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-TFPI antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-TFPI antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Anti-TFPI Antibody, clone 5J8X8, Rabbit Monoclonal, ,
Species Reactivity
human
Application
western blot
Anti-Tissue Factor Pathway Inhibitor antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot