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Merck

TAB2

TGF-beta activated kinase 1/MAP3K7 binding protein 2

Synonyms:
CHTD2, MAP3K7IP2
Species:
UniProtKB ID:
Gene ID:
  • Human(23118) Summary: The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. [provided by RefSeq, Jul 2008]
  • Mouse(68652) TGF-beta activated kinase 1/MAP3K7 binding protein 2
  • Rat(308267) TGF-beta activated kinase 1/MAP3K7 binding protein 2
  • dog(484028) TGF-beta activated kinase 1/MAP3K7 binding protein 2
  • chicken(421622) TGF-beta activated kinase 1/MAP3K7 binding protein 2
  • Zebrafish(494163) TGF-beta activated kinase 1/MAP3K7 binding protein 2
  • fruit fly(37216) TAK1-associated binding protein 2
  • naked mole-rat(101698406) TGF-beta activated kinase 1/MAP3K7 binding protein 2
  • domestic guinea pig(100717911) TGF-beta activated kinase 1/MAP3K7 binding protein 2
  • sheep(101122114) TGF-beta activated kinase 1/MAP3K7 binding protein 2
  • cow(540203) TGF-beta activated kinase 1/MAP3K7 binding protein 2
  • Horse(100060433) TGF-beta activated kinase 1/MAP3K7 binding protein 2
  • domestic cat(101098714) TGF-beta activated kinase 1/MAP3K7 binding protein 2

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TAB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-TAB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-TAB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human TAB2,
Species
human