OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
CLEC8A, LOX1, LOXIN, SCARE1, SLOX1
Human OLR1 (4973), Mouse Olr1 (108078), Rat Olr1 (140914), naked mole-rat Olr1 (101710182), domestic guinea pig Olr1 (100725301), domestic cat OLR1 (101086238), dog OLR1 (486694), sheep OLR1 (101117918), cow OLR1 (281368)
- Human(4973) Summary: This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
- Mouse(108078) oxidized low density lipoprotein (lectin-like) receptor 1
- Rat(140914) oxidized low density lipoprotein (lectin-like) receptor 1
- naked mole-rat(101710182) oxidized low density lipoprotein (lectin-like) receptor 1
- domestic guinea pig(100725301) oxidized low density lipoprotein (lectin-like) receptor 1
- domestic cat(101086238) oxidized low density lipoprotein (lectin-like) receptor 1
- dog(486694) oxidized low density lipoprotein (lectin-like) receptor 1
- sheep(101117918) oxidized low density lipoprotein (lectin-like) receptor 1
- cow(281368) oxidized low density lipoprotein (lectin-like) receptor 1
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