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NMNAT1

nicotinamide nucleotide adenylyltransferase 1

Synonyms:
LCA9, NMNAT, PNAT1
Species:
UniProtKB ID:
Gene ID:
  • Human(64802) Summary: This gene encodes an enzyme which catalyzes a key step in the biosynthesis of the coenzyme NAD. The encoded protein is one of several nicotinamide nucleotide adenylyltransferases. Studies in Drosophila and mammalian neurons have shown the encoded protein can confer protection to damaged neurons. This protection requires enzymatic activity which increases NAD levels and activates a nuclear deacetylase which is the protective molecule. Pseudogenes of this gene are located on chromosomes 1, 3, 4, 14 and 15. [provided by RefSeq, Dec 2011]
  • Mouse(66454) nicotinamide nucleotide adenylyltransferase 1
  • Rat(298653) nicotinamide nucleotide adenylyltransferase 1
  • cow(522863) nicotinamide nucleotide adenylyltransferase 1
  • naked mole-rat(101708976) nicotinamide nucleotide adenylyltransferase 1
  • Zebrafish(550322) nicotinamide nucleotide adenylyltransferase 1
  • sheep(101116072) nicotinamide nucleotide adenylyltransferase 1
  • chicken(419446) nicotinamide nucleotide adenylyltransferase 1
  • chicken(101669319) nicotinamide nucleotide adenylyltransferase 1
  • chicken(101748948) nicotinamide nucleotide adenylyltransferase 1
  • dog(479601) nicotinamide nucleotide adenylyltransferase 1
  • domestic cat(101094771) nicotinamide nucleotide adenylyltransferase 1
  • domestic guinea pig(100727955) nicotinamide nucleotide adenylyltransferase 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-NMNAT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-NMNAT1, IgG fraction of antiserum,
Species Reactivity
guinea pig, human, mouse, rabbit, rat
Application
western blot

Proteins

Product Number
Description
Species
NMNAT1 human, recombinant, expressed in E. coli, His tagged, >95% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human NMNAT1,
Species
human
MISSION® esiRNA, targeting mouse Nmnat1,
Species
mouse