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Merck

KLK3

kallikrein-related peptidase 3

Synonyms:
APS, KLK2A1, PSA, hK3
Species:
Human KLK3 (354)
UniProtKB ID:
P07288, C9JXH3, G3V0H4, G3XAE3, Q15096, Q16272, Q86TG8, Q8IXI4
Gene ID:
  • Human(354) Summary: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB5300268
Monoclonal Anti-KLK3 antibody produced in mouse, clone 5A11E9, ascites fluid,
Species Reactivity
human
Application
ELISA
flow cytometry
immunohistochemistry
western blot
AMAB91569
Monoclonal Anti-KLK3 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL9422, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
AMAB91567
Monoclonal Anti-KLK3 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL9414, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
HPA000764
Anti-KLK3 antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
SAB4702007
Monoclonal Anti-PSA Biotin produced in mouse, ,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
P3235
Prostate Specific Antigen from human semen, buffered aqueous solution,
Species
human
P3338
Prostate Specific Antigen from human semen, buffered aqueous solution,
Species
human
SRP6058
Kallikrein-3 human, recombinant, expressed in human cells, ≥95% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
EHU156951
MISSION® esiRNA, targeting human KLK3,
Species
human