IL1RAP
interleukin 1 receptor accessory protein
- Human(3556) Summary: Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Nov 2009]
- Mouse(16180) interleukin 1 receptor accessory protein
- Rat(25466) interleukin 1 receptor accessory protein
- naked mole-rat(101707386) interleukin 1 receptor accessory protein
- Horse(100068726) interleukin 1 receptor accessory protein
- domestic cat(101094125) interleukin 1 receptor accessory protein
- Domestic Rabbit(100341281) interleukin 1 receptor accessory protein
- sheep(101108354) interleukin 1 receptor accessory protein
- chicken(424908) interleukin 1 receptor accessory protein
- domestic guinea pig(100714704) interleukin 1 receptor accessory protein
- dog(488126) interleukin 1 receptor accessory protein
- cow(539334) interleukin 1 receptor accessory protein
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