IL10
interleukin 10
Synonyms:
CSIF, GVHDS, IL-10, IL10A, TGIF
Species:
Human IL10 (3586), Mouse Il10 (16153), Rat Il10 (25325), domestic guinea pig Il10 (100135553), domestic guinea pig Il10 (100715618), Zebrafish il10 (553957), chicken IL10 (428264), domestic cat IL10 (493683), dog IL10 (403628), cow IL10 (281246) ...More
UniProtKB ID:
Gene ID:
- Human(3586) Summary: The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]
- Mouse(16153) interleukin 10
- Rat(25325) interleukin 10
- domestic guinea pig(100135553) interleukin 10
- domestic guinea pig(100715618) interleukin 10
- Zebrafish(553957) interleukin 10
- chicken(428264) interleukin 10
- domestic cat(493683) interleukin 10
- dog(403628) interleukin 10
- cow(281246) interleukin 10
- Goat(100860746) interleukin 10
- Horse(100034187) interleukin 10
- sheep(443342) interleukin 10
- Domestic Rabbit(100008701) interleukin 10
- naked mole-rat(101708273) interleukin 10
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ELISA
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-IL10 antibody produced in mouse, clone 1C10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-Interleukin-10 antibody produced in goat, IgG fraction of antiserum, lyophilized powder,
Species Reactivity
mouse
Application
neutralization
western blot
western blot
Anti-IL-10 Antibody, clone 1O10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Anti-Interleukin-10 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse
Application
western blot
Anti-IL10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Proteins
Product Number
Description
Species
Interleukin-10/Fc Chimera (non-lytic) human, >98% (SDS-PAGE), recombinant, expressed in NS.1 cells, buffered aqueous solution,
Species
human
IL-10 human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human
Interleukin-10 human, IL-10, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture,
Species
human
Interleukin-10 from mouse, >97% (SDS-PAGE), recombinant, expressed in E. coli, suitable for cell culture,
Species
mouse
Interleukin-10 from rat, >95% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder,
Species
rat
esiRNA
Product Number
Description
Species