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Merck

GRIN2A

glutamate receptor, ionotropic, N-methyl D-aspartate 2A

Synonyms:
EPND, GluN2A, NMDAR2A, NR2A
Species:
UniProtKB ID:
Gene ID:
  • Human(2903) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(14811) glutamate receptor, ionotropic, NMDA2A (epsilon 1)
  • Rat(24409) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • sheep(101106989) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic guinea pig(100727265) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • dog(490012) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • chicken(427678) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic cat(101086110) glutamate receptor, ionotropic, N-methyl D-aspartate 2A

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Small Molecule - Agonist

Product Number
Description
Species
1,4-Bis(3-aminopropyl)piperazine, ≥99%,
Species
rat
Reversin 121, ≥97% (HPLC), powder,
Species
mouse, rat, human
ATPA, solid,
Species
human, rat
D-2-Aminoadipic acid, ,
Species
rat
D-Cycloserine, synthetic,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
4-Aminopiperidine, ,
Species
rat
Kainic acid monohydrate, ≥99% (TLC),
Species
human, mouse, rat
Acamprosate calcium, ≥98% (HPLC), powder,
Species
human
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Species
human
Acamprosate calcium, British Pharmacopoeia (BP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Glycine, puriss. p.a., reag. Ph. Eur., buffer substance, 99.7-101% (calc. to the dried substance),
Species
rat
Glycine, BioUltra, for molecular biology, ≥99.0% (NT),
Species
rat
1-Adamantylamine, 97%,
Species
human
Glycine, ACS reagent, ≥98.5%,
Species
rat
1-Adamantanemethylamine, 98%,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-GRIN2A antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-NMDAR2A Antibody, Chemicon®, from rabbit,
Species Reactivity
fish, human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Monoclonal Anti-Glun2A/Nr2A - Rpe antibody produced in mouse, clone S327-95, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry

western blot
Monoclonal Anti-Glun2A/Nr2A - Rpe antibody produced in mouse, clone S327A-38, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-Glun2A/Nr2A - Apc antibody produced in mouse, clone S327-95, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry

western blot

Small Molecule - Blocker

Product Number
Description
Species
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
Species
human
Agmatine sulfate salt, ≥97%, powder,
Species
human
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Orphenadrine hydrochloride, ≥98.0% (AT),
Species
human
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
Indole-2-carboxylic acid, 98%,
Species
rat, human
1,3-Diphenylguanidine, 97%,
Species
rat, mouse, human
Quisqualic acid, powder,
Species
rat
Nω-Nitro-L-arginine, ≥98% (TLC),
Species
rat, mouse, human
Pentamidine isethionate salt, powder,
Species
human

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
N-Methyl-1,3-diaminopropane, 98%,
Species
rat
4-Amino-2,2,6,6-tetramethylpiperidine, 98%,
Species
rat
1,3-Diamino-2-propanol, purum, ≥96.5% (GC),
Species
rat
N,N,2,2-Tetramethyl-1,3-propanediamine, 97%,
Species
rat
N,N,N′,N′-Tetramethyl-1,3-propanediamine, ≥99%,
Species
rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Grin2a,
Species
mouse
MISSION® esiRNA, targeting human GRIN2A,
Species
human