GDNF
glial cell derived neurotrophic factor
Synonyms:
ATF1, ATF2, HFB1-GDNF, HSCR3
Species:
Human GDNF (2668), Mouse Gdnf (14573), Rat Gdnf (25453), chicken GDNF (395569), sheep GDNF (101117619), naked mole-rat Gdnf (101700544), domestic cat GDNF (101097871), dog GDNF (489224), domestic guinea pig Gdnf (100717276), cow GDNF (386587)
UniProtKB ID:
Gene ID:
- Human(2668) Summary: This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene may be associated with Hirschsprung disease. [provided by RefSeq, Jun 2010]
- Mouse(14573) glial cell line derived neurotrophic factor
- Rat(25453) glial cell derived neurotrophic factor
- chicken(395569) glial cell derived neurotrophic factor
- sheep(101117619) glial cell derived neurotrophic factor
- naked mole-rat(101700544) glial cell derived neurotrophic factor
- domestic cat(101097871) glial cell derived neurotrophic factor
- dog(489224) glial cell derived neurotrophic factor
- domestic guinea pig(100717276) glial cell derived neurotrophic factor
- cow(386587) glial cell derived neurotrophic factor
- Horse(100067053) glial cell derived neurotrophic factor
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ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-GDNF antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-Glial Cell-derived Neurotrophic Factor (GDNF) antibody produced in goat, IgG fraction of antiserum, lyophilized powder,
Species Reactivity
human
Application
neutralization
Anti-Glial Derived Neurotrophic Factor Antibody, Chemicon®, from sheep,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
Anti-Glial Derived Neurotrophic Factor Antibody, serum, Chemicon®,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-Glial Derived Neurotrophic Factor Antibody, Chemicon®, from chicken,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Proteins
Product Number
Description
Species
GDNF from mouse, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
mouse
Glial Cell Line-derived Neurotrophic Factor human, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, ≥98% (SDS-PAGE),
Species
human
GDNF from rat, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
rat
esiRNA
Product Number
Description
Species