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Merck

GABRQ

gamma-aminobutyric acid (GABA) A receptor, theta

Synonyms:
THETA
Species:
UniProtKB ID:
Gene ID:
  • Human(55879) Summary: The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes the theta subunit of the GABA A receptor. The gene is mapped to chromosome Xq28 in a cluster of genes including those that encode the alpha 3 and epsilon subunits of the GABA A receptor. This gene location is also the candidate region of two different neurologic diseases: early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3). [provided by RefSeq, Nov 2009]
  • Mouse(57249) gamma-aminobutyric acid (GABA) A receptor, subunit theta
  • Rat(65187) gamma-aminobutyric acid (GABA) A receptor, theta
  • chicken(396288) gamma-aminobutyric acid (GABA) A receptor, theta
  • Horse(100063455) gamma-aminobutyric acid (GABA) A receptor, theta
  • cow(527180) gamma-aminobutyric acid (GABA) receptor, theta
  • dog(492225) gamma-aminobutyric acid (GABA) A receptor, theta
  • sheep(101113305) gamma-aminobutyric acid (GABA) A receptor, theta
  • domestic cat(101099698) gamma-aminobutyric acid (GABA) A receptor, theta
  • domestic guinea pig(100729123) gamma-aminobutyric acid (GABA) A receptor, theta
  • naked mole-rat(101714872) gamma-aminobutyric acid (GABA) A receptor, theta
  • Domestic Rabbit(100352807) gamma-aminobutyric acid (GABA) A receptor, theta

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Small Molecule - Agonist

Product Number
Description
Species
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
Etomidate, >98% (HPLC), powder,
Species
human
Etomidate, European Pharmacopoeia (EP) Reference Standard,
Species
human
Etomidate, United States Pharmacopeia (USP) Reference Standard,
Species
human
Ganaxolone, ≥98% (HPLC), solid,
Species
human, mouse
Isoflurane, ,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Flumazenil, United States Pharmacopeia (USP) Reference Standard,
Species
human
Ganaxolone, ≥98% (HPLC), solid,
Species
human, mouse
Flumazenil, >99% (HPLC), solid,
Species
rat, human
Acamprosate calcium, ≥98% (HPLC), powder,
Species
human
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Gabrq,
Species
mouse
MISSION® esiRNA, targeting human GABRQ (1),
Species
human
MISSION® esiRNA, targeting human GABRQ (2),
Species
human