CDH1
cadherin 1, type 1, E-cadherin (epithelial)
Synonyms:
Arc-1, CD324, CDHE, ECAD, LCAM, UVO
Species:
Human CDH1 (999), Mouse Cdh1 (12550), Rat Cdh1 (83502), dog CDH1 (442858), chicken CDH1 (415860), sheep CDH1 (100294601), domestic guinea pig Cdh1 (100726210), domestic cat CDH1 (101095391), sheep CDH1 (101119747), naked mole-rat Cdh1 (101719565) ...More
UniProtKB ID:
Gene ID:
- Human(999) Summary: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]
- Mouse(12550) cadherin 1
- Rat(83502) cadherin 1
- dog(442858) cadherin 1, type 1, E-cadherin (epithelial)
- chicken(415860) cadherin 1, type 1, E-cadherin (epithelial)
- sheep(100294601) cadherin 1, type 1, E-cadherin (epithelial)
- domestic guinea pig(100726210) cadherin 1, type 1, E-cadherin (epithelial)
- domestic cat(101095391) cadherin 1, type 1, E-cadherin (epithelial)
- sheep(101119747) cadherin 1, type 1, E-cadherin (epithelial)
- naked mole-rat(101719565) cadherin 1, type 1, E-cadherin (epithelial)
- Zebrafish(114424) cadherin 1, epithelial
- cow(282637) cadherin 1, type 1, E-cadherin (epithelial)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CD324-PE antibody produced in mouse, clone 67A4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-Cadherin-pan antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-E-Cadherin Antibody, clone 2Q9Y7, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-E-Cadherin (CDH1) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM244, purified immunoglobulin,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-E-Cadherin Antibody, clone 67A4, clone 67A4, Chemicon®, from mouse,
Species Reactivity
human
Application
flow cytometry
western blot
western blot
Proteins
Product Number
Description
Species