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Merck

ADAMTS10

ADAM metallopeptidase with thrombospondin type 1 motif, 10

Synonyms:
ADAM-TS10, ADAMTS-10, WMS, WMS1
Species:
UniProtKB ID:
Gene ID:
  • Human(81794) Summary: This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq, Jul 2008]
  • Mouse(224697) a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10
  • Rat(314655) ADAM metallopeptidase with thrombospondin type 1 motif, 10
  • naked mole-rat(101722293) ADAM metallopeptidase with thrombospondin type 1 motif, 10
  • sheep(101105076) ADAM metallopeptidase with thrombospondin type 1 motif, 10
  • Domestic Rabbit(100354233) ADAM metallopeptidase with thrombospondin type 1 motif, 10
  • dog(611267) ADAM metallopeptidase with thrombospondin type 1 motif, 10
  • cow(513140) ADAM metallopeptidase with thrombospondin type 1 motif, 10
  • domestic cat(101092419) ADAM metallopeptidase with thrombospondin type 1 motif, 10
  • chicken(769592) ADAM metallopeptidase with thrombospondin type 1 motif, 10
  • domestic guinea pig(100734296) ADAM metallopeptidase with thrombospondin type 1 motif, 10
  • Zebrafish(564734) ADAM metallopeptidase with thrombospondin type 1 motif, 10

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ADAMTS10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ADAMTS10,
Species
human