Safety Inside
Risk Prevention, Daily Safety, Emergency Help
TRUST OUR LAB SAFETY EXPERTISE
Working in the lab always poses risks of exposure to hazardous chemicals. However, proactively following lab safety standards for risk prevention, daily safety, and emergency help in handling hazardous materials will keep you safe, simplify your work, and help you save resources.
Safety videos & Webinars
RISK ASSESSMENT FOR CARCINOGENIC SUBSTANCES
Take a deep dive into identifying carcinogens, STOP hierarchy of protective measures, and the special approach in lab for risk assessment and documentation of risk assessment.
SUBSTITUTING HAZARDOUS SUBSTANCES
Using safer alternatives in the lab reduces risk and minimizes exposure to hazardous materials. Take a deep dive into identifying hazardous substances, risk assessment, how mistakes can be avoided, and what to do if no substitution is possible. Learn how to conduct a legally compliant substitution check using real substances as examples.
SAFETY IN THE LABORATORY
The video offers a thorough overview of general lab safety, covering packaging, storage, and chemical handling. It includes essential information like labels, safety data sheets, and lab rules. You'll learn proper use of personal protective equipment and withdrawal systems for enhanced safety. It also provides insights on preventing electrostatic explosions.
CHEMICAL SAFETY IN PRACTICE
Learn the most important lab safety rules when working with hazardous materials. Integrate safety right from the start with safety, packaging, and convenient tools to minimize the chance of lab accidents. Quickly react to chemical spillage with the right products swiftly and efficiently.
The pharmaceutical industry heightened its concern about nitrosamines, particularly N-nitrosodimethylamine (NDMA), after its discovery in valsartan in July 2018. This triggered recalls of angiotensin II receptor blocker medications, leading to increased scrutiny for nitrosamine impurities in drug products. Multiple factors, including degradation processes, contaminated raw materials, solvents, and reagents, contribute to the presence of these "unintended" organic impurities in pharmaceuticals.
Classified as Class 1 impurities, these N-nitrosamines are designated as "cohort of concern" compounds and "known mutagenic carcinogens" by the ICH Guideline M7(R1). Additionally, they are classified as 2A–Probable Carcinogens by the International Agency for Cancer Research (IARC), highlighting the critical need for rigorous nitrosamines analysis in the pharmaceutical industry.
The FDA’s list of nitrosamine impurities, including NDMA, NDEA (N-nitrosodiethylamine), NIEPA, NDIPA, NDBA (N-nitrosodibutylamine), and NMBA, highlights NDMA and NDEA as the most prevalent nitrosamines in drugs. Current regulatory restrictions allow only very low levels, requiring highly sensitive analytical techniques for detection.
We offer a comprehensive portfolio of nitrosamine testing products, supported by detailed application guidelines, ensuring reliable detection of these carcinogenic nitrosamines using LC-MS or GC-MS methodologies.
RISK PREVENTION IN LAB
Preventing harm starts with the right packaging and materials. Our unrivaled safety standards and application-oriented foresight in designing specially developed packaging materials ensures you work safely in the lab.
Enjoy reliable, sustainable cleaning power with our non-toxic, biodegradable detergents
Our orange gel contains an indicator based on iron-salt instead of the carcinogenic cobalt dichloride used in blue silica gel
Our PE-coated glass bottles protect you from splinters and chemical burns in case of accidents
Safe handling of chemicals by utilizing special lightweight, unbreakable and protective properties of certain packaging materials.
DAILY LAB SAFETY
Handling hazardous goods in the lab safely is a challenge, even for routine lab work. We make it easy with our compatible chemical components, packaging, safety tools, and withdrawal systems so you can focus on your highly sensitive applications.
Safe Handling
Handling hazardous chemicals safely is always a challenge in daily lab work. We make it easy!
Safety Accessories
Benefit from ingenious but simple accessories that instantly increase your level of protection from the first use to prevent accidental contact with hazardous chemicals.
EMERGENCY HELP FOR LAB SPILLAGES
Lab accidents can happen at any time. It is important to act quickly but wisely. With the Chemizorb® range, we offer a one-stop-solution for rapid, reliable absorbance and neutralization of liquid chemical spills.
Spillage Absorption
Make use of dedicated absorbents to clear away chemical spillages in a quick, safe, and environmentally friendly way. Explore the variety of absorbents for different types of chemical spills.
Related Product Resources
- Make use of our Acids in Safebreak bottles
Meet our highly effective and protective solution for acids: The Safebreak bottle. Safebreak is a unique glass bottle that is coated with polyethylene (PE).
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- Learn more about our ingenious safety solutions for safe handling of hazardous substances.
The “Safety Connects” brochure by Sigma-Aldrich emphasizes the importance of safety in daily solvent handling. It details their investment in safe, innovative solvent handling technology and product development, focusing on user safety and reliable analytical results.
- Clear away chemical spillages in a quick, safe, and environmentally friendly way.
Supelco® Chemizorb® absorbents, you can clear away aggressive or unpleasant liquids quickly and safely. Our fast-acting absorbents consist of porous mineral or synthetic copolymers that are chemically inert, and capable of absorbing up to 400% of their own weight in liquid.
- Find the right withdrawal systems and safety accessories for handling acids & bases.
The best way to protect yourself from unintended contact with acids and bases is through the use of suitable withdrawal systems. Our unique solutions allow you to safely and easily dispense harmful chemicals from large containers into other, typically smaller, reaction vessels, thereby minimizing risks.
- Find the perfect solution to cleaning your lab equipment with Extran® labware detergents
Thorough, residue-free cleaning is essential for reliable processes. This applies to both: laboratories and production facilities. Everything that comes into contact with chemicals or biological substances must be free of impurities, both before and after use.
- Explore the extensive portfolio of reliable drying agents.
. Our comprehensive portfolio offers user-friendly solutions for a wide range of applications – from drying gases, liquids or solids using static or dynamic drying processes, to protecting sensitive goods and materials from moisture, mold or corrosion.
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