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1448005

USP

Morphine sulfate

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Morphine sulfate salt pentahydrate, Morphine hemi[sulfate pentahydrate]

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About This Item

Empirical Formula (Hill Notation):
C34H40N2O10S · 5H2O
CAS Number:
Molecular Weight:
758.83
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

morphine

manufacturer/tradename

USP

drug control

USDEA Schedule II; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

O.O.O.O.O.OS(O)(=O)=O.CN1CC[C@]23[C@H]4Oc5c(O)ccc(C[C@@H]1[C@@H]2C=C[C@@H]4O)c35.CN6CC[C@]78[C@H]9Oc%10c(O)ccc(C[C@@H]6[C@@H]7C=C[C@@H]9O)c8%10

InChI

1S/2C17H19NO3.H2O4S.5H2O/c2*1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18;1-5(2,3)4;;;;;/h2*2-5,10-11,13,16,19-20H,6-8H2,1H3;(H2,1,2,3,4);5*1H2/t2*10-,11+,13-,16-,17-;;;;;;/m00....../s1

InChI key

GRVOTVYEFDAHCL-RTSZDRIGSA-N

Gene Information

human ... OPRM1(4988)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets, has been developed and issued under the Authority of the issuing Pharmacopoeia.

For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Morphine sulfate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Morphine Sulfate Injection
  • Morphine Sulfate Compounded Suppositories
  • Morphine Sulfate Compounded Injection
  • Morphine Sulfate Extended-Release Capsules
  • Morphine Sulfate Compounded Oral Solution
  • Dihydrocodeine Bitartrate

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Morphine Sulfate Compounded Suppositories
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 40(6), 3028-3028 (2016)
Morphine Sulfate Injection
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 37(3), 3027-3027 (2018)
Hydromorphone Hydrochloride Tablets
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 2254-2254 (2013)
Dihydrocodeine Bitartrate
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 43(3), 1386-1386 (2019)
Morphine Sulfate
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 48(3), 3023-3023 (2020)

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