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Key Documents

SML3611

Sigma-Aldrich

Rubusoside

≥95% (HPLC)

Synonym(s):

(4α)-13-(β-D-Glucopyranosyloxy)-kaur-16-en-18-oic acid β-D-glucopyranosyl ester

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About This Item

Empirical Formula (Hill Notation):
C32H50O13
CAS Number:
Molecular Weight:
642.73
UNSPSC Code:
12352200
NACRES:
NA.25

Quality Level

Assay

≥95% (HPLC)

form

powder

optical activity

[α]/D -37 to -47°, c = 0.5 in methanol

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

SMILES string

C=C1[C@@]2(O[C@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O3)C[C@]4(C1)CC[C@]5([H])[C@](C)(C(O[C@H]6[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O6)=O)CCC[C@@]5(C)[C@]4([H])CC2

Biochem/physiol Actions

Rubusoside is a natural next generation sugar substitute isolated from Rubus suavissimus S. Lee. Rubusoside exhibits antiangiogenic and antiallergic properties. It can be used as a solubilizing agent for assorted biologically active agents.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Chengqiang Wang et al.
Journal of food biochemistry, 44(5), e13187-e13187 (2020-03-19)
The anti-inflammatory and anti-asthmatic effects of rubusoside (Rbs) were investigated in the ovalbumin (OVA)-induced asthmatic mice, followed by effective attenuation of Rbs treatment on the airway hyperresponsiveness and reduction of inflammatory cells inside the bronchoalveolar lavage fluid (BALF). The mitigation
Sachin K Khiste et al.
Molecular cancer therapeutics, 19(2), 564-574 (2019-10-28)
Ceramide (Cer) is an active cellular sphingolipid that can induce apoptosis or proliferation-arrest of cancer cells. Nanoparticle-based delivery offers an effective approach for overcoming bioavailability and biopharmaceutics issues attributable to the pronounced hydrophobicity of Cer. Missense mutations of the protein
Chunru Guan et al.
Applied and environmental microbiology, 86(16) (2020-06-07)
Dental caries is a biofilm-mediated disease in which Streptococcus mutans is the main pathogenic microorganism, and its incidence is closely related to sucrose. Rubusoside is a natural nonnutritive sweetener isolated from Rubus suavissimus S. Lee. This study was designed to

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