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SML3590

Sigma-Aldrich

Benzonatate

≥98% (HPLC)

Synonym(s):

4-​(Butylamino)​-benzoic acid 3,​6,​9,​12,​15,​18,​21,​24,​27-​nonaoxaoctacos-​1-​yl ester

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About This Item

Empirical Formula (Hill Notation):
C30H53NO11
CAS Number:
Molecular Weight:
603.74
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.25

Quality Level

Assay

≥98% (HPLC)

form

oil

storage condition

desiccated

color

colorless to orange

storage temp.

-10 to -25°C

Biochem/physiol Actions

Benzonatate is a non-narcotic antitussive medication with sodium channel-blocking properties. Benzonatate is a ligand of both central and peripheral respiratory mucosal stretch receptors.

Caution

Hygroscopic

Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Chronic 3

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Use of a nonnarcotic antitussive for severe, treatment-resistant oral ulcers.
Melissa Danesh et al.
Journal of the American Academy of Dermatology, 72(6), e159-e159 (2015-05-20)
Mark L Winter et al.
Journal of medical toxicology : official journal of the American College of Medical Toxicology, 6(4), 398-402 (2010-05-22)
Little has been published on benzonatate ingestion, with the few case reports suggesting significant risk of seizures after poisoning. A 7-year retrospective review of all single substance ingestion of benzonatate reported to the National Poison Center Database System (NPDS) from

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