P5177

Methyl palmitate

≥99% (capillary GC)

• Synonym(s): n-Hexadecanoic acid methyl ester, Methyl hexadecanoate, Palmitic acid methyl ester
• Linear Formula: CH₃(CH₂)₁₄CO₂CH₃
• CAS Number: 112-39-0
• Molecular Weight: 270.45
• Beilstein: 1780973
• EC Number: 203-966-3
• MDL number: MFCD00008994
• UNSPSC Code: 12352211
• PubChem Substance ID: 24898607
• NACRES: NA.25

Properties

• biological source: plant (palm)
• Assay: ≥99% (capillary GC)
• form: solid
• refractive index: n20/D 1.4512 (lit.)
• bp: 185 °C/10 mmHg (lit.)
• mp: 32-35 °C (lit.)
• density: 0.852 g/mL at 25 °C (lit.)
• functional group: ester
• lipid type: saturated FAs
• shipped in: ambient
• storage temp.: 2-8°C
• SMILES string: CCCCCCCCCCCCCCCC(=O)OC
• InChI: 1S/C17H34O2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17(18)19-2/h3-16H2,1-2H3
• InChI key: FLIACVVOZYBSBS-UHFFFAOYSA-N
• Gene Information: human ... CNR1(1268) , CNR2(1269) ; rat ... Faah(29347)

Description

General description

Methyl palmitate (PAME), a fatty acid ester of palmitic acid, is a muscurinic receptors antagonist. Methyl palmitate functions as a vasodilator and relaxes the arterioles in retina upon electrical depolarization. In the superior cervical ganglion, methyl palmitate modulates nicotinic receptor. Endogenous methyl palmitate modulates nicotinic receptor-mediated transmission in the superior cervical ganglion. PAME activates Kv7 channels and promotes perivascular adipose tissue.

Application

Methyl palmitate has been used to test impact of cerebral blood flow using laser doppler flowmetry (LDF) experiments and as a standard to determine retention indices (RIs) using gas chromatograph−mass spectrometer

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): 235.4 °F - closed cup
• Flash Point(C): 113.0 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves