F7879
Ferritin, cationized from horse spleen
10 mg/mL in 0.15 M NaCl
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Recommended Products
biological source
horse spleen
Quality Level
sterility
sterile-filtered
form
liquid
concentration
10 mg/mL in 0.15 M NaCl
technique(s)
cell culture | mammalian: suitable
electron microscopy: suitable
UniProt accession no.
storage temp.
2-8°C
Gene Information
horse ... FTL(100051593)
General description
Ferritin, an iron-storage protein is usually present in the liver and spleen in mammals. Iron and ferritin are distributed relatively same in the eye. Ferritin is made up of heavy and light chains.
Application
A cationic derivative used to label negatively charged cell membranes for visualization by electron microscopy.
Ferritin is an iron storage protein that plays a central role in iron metabolism, and may be elevated in inflammatory or malignant diseases. It has been used in studies as an indicator of body iron supply, but may prove inaccurate in in the presence of chronic inflammation.
Ferritin, cationized from horse spleen has been used:
- to incubate amoebae (106) in the study, to determine whether trophozoites are able to take up ferritin and internalise this protein for their growth in axenic culture
- to determine phagosome-lysosome fusion by electron microscopy
- to label freshly excised chick optic tecta in serum free incubation medium
Biochem/physiol Actions
Ferritin holds iron at its ferric state (Fe3+). The core of ferritin has the capability to hold 4500 iron molecules. It is essential to store iron in vertebrates. Ferritin is also essential to store and transport iron in invertebrates. It plays a key role in dietary iron absorption.
Preparation Note
Prepared by coupling horse spleen ferritin with N,N-dimethyl-1,3-propanediamine (DMPA).
Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
Use of cationized ferritin as a label of negative charges on cell surfaces.
D Danon et al.
Journal of ultrastructure research, 38(5), 500-510 (1972-03-01)
Jennifer R Charlton et al.
American journal of physiology. Renal physiology, 321(3), F293-F304 (2021-07-21)
Kidney pathologies are often highly heterogeneous. To comprehensively understand kidney structure and pathology, it is critical to develop tools to map tissue microstructure in the context of the whole, intact organ. Magnetic resonance imaging (MRI) can provide a unique, three-dimensional
Iron-Induced Retinal Damage
Handbook of nutrition, diet, and the eye, 619-626 (2014)
Ferritin
Reference Module in Life Sciences (2017)
Maria Jose Uria et al.
The Journal of experimental medicine, 205(6), 1423-1434 (2008-05-28)
The presence of serum bactericidal antibodies is a proven correlate of protection against systemic infection with the important human pathogen Neisseria meningitidis. We have identified three serogroup C N. meningitidis (MenC) isolates recovered from patients with invasive meningococcal disease that
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service