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07076

Sigma-Aldrich

Castor Oil, Hydrogenated,Ethoxylated

Synonym(s):

Cremophor® RH 40, Macrogolglycerol hydroxystearate, PEG-40 castor oil, Polyoxyl 40 hydrogenated castor oil, RH 40

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About This Item

CAS Number:
61788-85-0
MDL number:
MFCD01771439
UNSPSC Code:
12161900
NACRES:
NA.25

impurities

≤0.2% sulfated ash (verfied on random samples only)
≤1 ppm ethylene oxide
≤10 ppm dioxan
≤10 ppm heavy metals (verfied on random samples only)
≤2 ppm arsenic (verfied on random samples only)
≤2.0% water
≤5000 ppm acetic acid
≤620 ppm diethylene glycol
≤620 ppm ethylene glycol

ign. residue

≤0.25% (verfied onrandom samples only)

acid value

≤0.8 mg KOH/g

hydroxyl value

60‑75 mg KOH/g

iodine value

≤1.0 g I2/100 g

saponification value

50‑60 mg KOH/g

suitability

suitable for acidity or alkalinity

Related Categories

Application

Castor Oil, Hydrogenated,Ethoxylated is used to solubilize vitamins, water insoluble active substances and essential oils in water or mixtures of water and alcohol.

Other Notes

Castor Oil, Hydrogenated, Ethoxylated is the brand name for a range of non-ionic polyethoxylated detergents. It was developed for use as solubilizers and emulsifiers.

Analysis Note

congealing temperature 16-26°C

Legal Information

Cremophor is a registered trademark of BASF SE

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

467.6 °F

Flash Point(C)

242 °C

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Christofori M R R Nastiti et al.
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Masafumi Uematsu et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 27(5), 437-444 (2011-07-01)
To determine the element that modulates benzalkonium chloride (BAC) toxicity by using a new electrophysiological method to evaluate acute corneal barrier dysfunction induced by travoprost Z with sofZia (Travatan Z(®)), travoprost with 0.015% BAC (Travatan(®)), and its additives. Corneal transepithelial
Shoukath M Ali et al.
International immunopharmacology, 10(3), 325-330 (2009-12-23)
Develop Nanosomal formulation of Tacrolimus to provide safer alternative treatment for organ transplantation patients. Investigate safety, tolerability and pharmacokinetics of Nanosomal Tacrolimus formulation versus marketed Tacrolimus containing polyoxyl 60 hydrogenated castor oil (HCO-60) that causes side effects. Nanosomal Tacrolimus was
Allergic contact dermatitis to polyethylene glycol-7 hydrogenated castor oil.
M Kalavala et al.
Contact dermatitis, 56(5), 287-288 (2007-04-20)
William J Gradishar et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 23(31), 7794-7803 (2005-09-21)
ABI-007, the first biologically interactive albumin-bound paclitaxel in a nanameter particle, free of solvents, was compared with polyethylated castor oil-based standard paclitaxel in patients with metastatic breast cancer (MBC). This phase III study was performed to confirm preclinical studies demonstrating
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