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MAB8257

Sigma-Aldrich

Anti-Influenza A Antibody, nucleoprotein, clone A1

clone A1, Chemicon®, from mouse

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

A1, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunofluorescence: suitable

isotype

IgG2a

shipped in

wet ice

Specificity

Specific for the Influenza A nucleoprotein. Has stronger binding with N1-type Flu A. No cross reactivity seen to influenza B or other respiratory viruses. Shown to react with Avian H5N1 strain. No reactivity seen to influenza B or other respiratory viruses.

Immunogen

Epitope: nucleoprotein
Influenza A

Application

Anti-Influenza A Antibody, nucleoprotein, clone A1 detects level of Influenza A & has been published & validated for use in IF.
Indirect Immunofluorescence of acetone fixed specimens.

Optimal working dilutions must be determined by the end user.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral

Physical form

Format: Purified
Protein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with 0.1% sodium azide as a preservative.
Protein A purified

Storage and Stability

Maintain for 1 year at 2–8°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Analysis Note

Control
Influenza Control Slides, Catalogue Number 5010-5

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Henry Memczak et al.
PloS one, 11(7), e0159074-e0159074 (2016-07-16)
Antibodies against spike proteins of influenza are used as a tool for characterization of viruses and therapeutic approaches. However, development, production and quality control of antibodies is expensive and time consuming. To circumvent these difficulties, three peptides were derived from
Evaluation of an epitope-blocking enzyme-linked immunosorbent assay for the detection of antibodies to influenza A virus in domestic and wild avian and mammalian species.
Heather J Sullivan,Bradley J Blitvich,Kaci VanDalen,Kevin T Bentler,Alan B Franklin,J Jeffrey Root
Journal of Virological Methods null
Jutatip Panaampon et al.
PloS one, 7(5), e36318-e36318 (2012-05-09)
In this study, the effect of innate serum inhibitors on influenza virus infection was addressed. Seasonal influenza A(H1N1) and A(H3N2), 2009 pandemic A(H1N1) (H1N1pdm) and highly pathogenic avian influenza (HPAI) A(H5N1) viruses were tested with guinea pig sera negative for
Evolution of H3N2 influenza virus in a guinea pig model.
Long, J; Bushnell, RV; Tobin, JK; Pan, K; Deem, MW; Nara, PL; Tobin, GJ
Testing null
Aftab Alam et al.
Neoplasia (New York, N.Y.), 21(10), 945-962 (2019-08-20)
Down-regulation or loss of MHC class I expression is a major mechanism used by cancer cells to evade immunosurveillance and increase their oncogenic potential. MHC I mediated antigen presentation is a complex regulatory process, controlled by antigen processing machinery (APM)

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