524624
Phosphatase Inhibitor Cocktail I
liquid, for the inhibition of alkaline phosphatases and serine/threonine protein phosphatases
Synonym(s):
Phosphatase inhibitor
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
UNSPSC Code:
12352200
NACRES:
NA.28
Recommended Products
product name
Phosphatase Inhibitor Cocktail Set I, Phosphatase Inhibitor Cocktail Set I contains three inhibitors that will inhibit alkaline phosphatases as well as serine/threonine protein phosphatases such as PP1 and PP2A.
Quality Level
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
shipped in
ambient
storage temp.
−20°C
General description
A cocktail of three inhibitors that will inhibit alkaline phosphatases as well as serine/threonine protein phosphatases such as PP1 and PP2A. This product is provided as a set of five 1 ml vials. Each vial contains 1 ml phosphatase inhibitor cocktail solubilized in DMSO with the following components: Bromotetramisole oxalate (2.5 mM), Cantharidin (Cat. No. 210155; 500 µM), and Microcystin-LR (Cat. No. 475815; 500 nM).
A cocktail of three inhibitors that will inhibit alkaline phosphatases as well as serine/threonine protein phosphatases such as PP1 and PP2A. This product is provided as a set of five 1 ml vials. May be used with cell lysates and tissue extracts, including samples containing detergents. Each vial contains 1 ml phosphatase inhibitor cocktail solubilized in DMSO with the following components:
Biochem/physiol Actions
Cell permeable: no
Primary Target
Alkaline phosphatases as well as serine/threonine protein phosphatases such as PP1 and PP2A
Alkaline phosphatases as well as serine/threonine protein phosphatases such as PP1 and PP2A
Product does not compete with ATP.
Reversible: no
Physical form
In DMSO.
Reconstitution
For long-term storage, aliquot and freeze (-20°C). Dilute 1:100 just prior to use.
Legal Information
Not available for sale outside of the United States.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
188.6 °F - closed cup - (Dimethylsulfoxide)
Flash Point(C)
87 °C - closed cup - (Dimethylsulfoxide)
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
An Phu Tran Nguyen et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(29), 17296-17307 (2020-07-08)
Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of late-onset, autosomal-dominant familial Parkinson's disease (PD). LRRK2 functions as both a kinase and GTPase, and PD-linked mutations are known to influence both enzymatic activities. While PD-linked LRRK2
Rama K Mishra et al.
Chemical biology & drug design, 94(4), 1813-1823 (2019-07-02)
Mnk kinases (Mnk1 and 2) are downstream effectors of Map kinase pathways and regulate phosphorylation of eukaryotic initiation factor 4E. Engagement of the Mnk pathway is critical in acute myeloid leukemia (AML) leukemogenesis and Mnk inhibitors have potent antileukemic properties
Agnes S Zybura et al.
The Journal of biological chemistry, 295(33), 11845-11865 (2020-07-03)
Nav1.6 is the primary voltage-gated sodium channel isoform expressed in mature axon initial segments and nodes, making it critical for initiation and propagation of neuronal impulses. Thus, Nav1.6 modulation and dysfunction may have profound effects on input-output properties of neurons
Aurore Thomazeau et al.
Molecular psychiatry (2020-07-02)
Many neurodevelopmental disorders are characterized by impaired functional synaptic plasticity and abnormal dendritic spine morphology, but little is known about how these are related. Previous work in the Fmr1-/y mouse model of fragile X (FX) suggests that increased constitutive dendritic
Tiffany A McLamarrah et al.
The Journal of cell biology, 219(2) (2019-12-17)
During centriole duplication, a preprocentriole forms at a single site on the mother centriole through a process that includes the hierarchical recruitment of a conserved set of proteins, including the Polo-like kinase 4 (Plk4), Ana2/STIL, and the cartwheel protein Sas6.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service