06-1367

Anti-SRp75 Antibody

from rabbit

• Synonym(s): serine/arginine-rich splicing factor 4, splicing factor, arginine/serine-rich 4, SR splicing factor 4, Pre-mRNA-splicing factor SRP75
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: purified antibody
• antibody product type: primary antibodies
• clone: polyclonal
• species reactivity: human, mouse, rat
• technique(s): western blot: suitable
• NCBI accession no.: NP_005617
• UniProt accession no.: Q08170
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... SRSF4(6429)

Description

General description

SRp75, also known as Serine/arginine-rich splicing factor 4, is an essential splicing factor that is a member of the SR family of proteins. This protein is a component of the pre-mRNA splicing complex and is believed to play a role in alternative splice site selection. Consistent with this excess levels of SRp75 have been shown to play a role in alternative splicing of CD45. SRp75 is normally found in the nucleus and is known to be hyperphosphorylated at serine residues in its RS domain.

Immunogen

KLH-conjugated linear peptide corresponding to human SRp75.

Application

Anti-SRp75 Antibody is a rabbit polyclonal antibody for detection of SRp75 also known as serine/arginine-rich splicing factor 4, SR splicing factor 4, Pre-mRNA-splicing factor SRP75 & has been validated in WB.

Immunoprecipitation Analysis: A reprentative lot of this antibody was used by an independent laboratory in IP. (Jiang, K., et al. (2009). Endocrinology. 150(5):2087-2097.)

Quality

Evaluated by Western Blot in L6 cell lysate.

Western Blot Analysis: 1:500 dilution of this antibody detected SRp75 on 10 µg of L6 cell lysate.

Target description

~ 62 kDa observed

Physical form

Format: Purified

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable