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Sigma-Aldrich

Heregulin-β3, Epidermal growth factor domain

liquid, suitable for cell culture

Synonym(s):

EGF Domain

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About This Item

UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.75

product name

Heregulin-β3, Epidermal growth factor (EGF) domain, The Heregulin-β3 protein, Epidermal growth factor (EGF) domain is available in a 100 µg format.

Quality Level

100

form

liquid

manufacturer/tradename

Upstate®

technique(s)

cell culture | mammalian: suitable

input

sample type mesenchymal stem cell(s)
sample type cardiac stem cell(s)

NCBI accession no.

NM_004495.2
NM_013956.2
NM_013957.2
NM_013958.2
NM_013959.2
NM_013960.2
NM_013961.2
NM_013962.2
NM_013964.2

UniProt accession no.

Q02297

shipped in

dry ice

Gene Information

human ... NRG1(3084)

Related Categories

General description

Product Source: Thrombin cleaved GST-fusion protein corresponding to the EGF domain (residues 178-241) of heregulin-beta 3.

Quality

Routinely evaluated by Receptor Activation Analysis.

Physical form

PBS with 30% glycerol. Liquid.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Certificates of Analysis (COA)

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L M Wang et al.
Proceedings of the National Academy of Sciences of the United States of America, 95(12), 6809-6814 (1998-06-17)
Interleukin 3-dependent murine 32D cells do not detectably express members of the ErbB receptor family and do not proliferate in response to known ligands for these receptors. 32D transfectants were generated expressing human ErbB4 alone (32D.E4) or with ErbB2 (32D.E2/E4).
M Alimandi et al.
The EMBO journal, 16(18), 5608-5617 (1997-10-06)
Interleukin-3 (IL-3)-dependent murine 32D cells do not detectably express epidermal growth factor receptors (EGFRs) and do not proliferate in response to EGF, heregulin (HRG) or other known EGF-like ligands. Here, we report that EGF specifically binds to and can be

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