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134708

Sigma-Aldrich

2-Bromo-2-nitro-1,3-propanediol

98%

Synonym(s):

BNPD, BNPK, Bronopol

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About This Item

Linear Formula:
HOCH2C(Br)(NO2)CH2OH
CAS Number:
Molecular Weight:
199.99
Beilstein:
1705868
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

98%

form

crystals

mp

130-133 °C (lit.)

solubility

H2O: soluble 100 mg/mL, clear, colorless to faintly yellow

SMILES string

OCC(Br)(CO)[N+]([O-])=O

InChI

1S/C3H6BrNO4/c4-3(1-6,2-7)5(8)9/h6-7H,1-2H2

InChI key

LVDKZNITIUWNER-UHFFFAOYSA-N

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Application

  • Effect of leave-on cosmetic antimicrobial preservatives on healthy skin resident Staphylococcus epidermidis.: This study examines the impact of various antimicrobial preservatives, including 2-Bromo-2-nitro-1,3-propanediol, on the microbiota of healthy skin, particularly focusing on Staphylococcus epidermidis. The findings suggest that such preservatives can influence the skin′s microbial balance, which is essential for maintaining skin health (Zhang et al., 2023).
  • Assessing the residual antibacterial activity of clinical materials disinfected with glutaraldehyde, o-phthalaldehyde, hydrogen peroxide or 2-bromo-2-nitro-1,3-propanediol by means of a bacterial toxicity assay.: This research assesses the residual antibacterial effects of various disinfectants, including 2-Bromo-2-nitro-1,3-propanediol, on clinical materials, contributing to improved disinfection protocols in healthcare settings (Lerones et al., 2004).
  • Development and testing of a microbiological assay to detect residual effects of disinfectant on hard surfaces.: This study developed a microbiological assay to evaluate the residual effects of disinfectants, including 2-Bromo-2-nitro-1,3-propanediol, on hard surfaces, aiming to enhance surface disinfection strategies in various industries (Mariscal et al., 1999).

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

4.1B - Flammable solid hazardous materials

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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2-Bromo-2-nitro-1, 3-propanediol (Bronopol) and its derivatives: Synthesis, properties, and application (a review).
Legin, G. Ya.
Pharmaceutical Chemistry Journal, 30(4), 273-284 (1996)
E Anne Greene et al.
Applied and environmental microbiology, 72(12), 7897-7901 (2006-09-26)
MICs of six broad-spectrum biocides and two specific metabolic inhibitors and fractional inhibitory concentration indexes (FICIs) for controlling a sulfide-producing consortium were determined. Nitrite was synergistic (FICI<1) with all but one biocide due to its specific inhibition of dissimilatory sulfite
Na Cui et al.
Environmental pollution (Barking, Essex : 1987), 159(2), 609-615 (2010-11-03)
Transformation products usually differ in environmental behaviors and toxicological properties from the parent contaminants, and probably cause potential risks to the environment. Toxicity evolution of a labile preservative, bronopol, upon primary aquatic degradation processes was investigated. Bronopol rapidly hydrolyzed in
D Sierra et al.
Journal of dairy science, 92(10), 4841-4845 (2009-09-19)
This study was designed to evaluate the effects of different storage conditions on total bacterial count (TBC) determinations made in goat bulk tank milk using an automated flow cytometry method. The storage conditions tested were storage temperature (refrigeration at 4
Andrew P Shinn et al.
Veterinary parasitology, 186(3-4), 229-236 (2011-12-14)
Pyceze™ (Novartis Animal Vaccines Ltd.) is licensed as a veterinary medicine to treat fungal infections in salmon, trout and their eggs. The active ingredient is bronopol, which due to its broad-spectrum activity has the potential to be an effective treatment

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