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1379183

USP

Melamine

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

2,4,6-Triamino-1,3,5-triazine, sym-Triaminotriazine

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About This Item

Empirical Formula (Hill Notation):
C3H6N6
CAS Number:
108-78-1
Molecular Weight:
126.12
Beilstein:
124341
MDL number:
MFCD00006055
UNSPSC Code:
41116107
PubChem Substance ID:
329750341
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

melamine

manufacturer/tradename

USP

mp

>300 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

Nc1nc(N)nc(N)n1

InChI

1S/C3H6N6/c4-1-7-2(5)9-3(6)8-1/h(H6,4,5,6,7,8,9)

InChI key

JDSHMPZPIAZGSV-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Melamine USP Reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monograph such as metformin Hydrochloride

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Pictograms

Health hazard
GHS08

Signal Word

Warning

Hazard Statements

H351,H361f,H373

Hazard Classifications

Carc. 2 - Repr. 2 - STOT RE 2

Target Organs

Urinary tract

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

572.0 °F - closed cup

Flash Point(C)

300 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yu-Chang Tyan et al.
Analytical and bioanalytical chemistry, 395(3), 729-735 (2009-08-12)
In the summer of 2008, serious illnesses and deaths of babies in China were linked to melamine-tainted powdered infant formula. Melamine contains several metabolites, such as ammeline, ammelide, and cyanuric acid, and has been used for the adulteration of foods
Michael F Neerman et al.
International journal of pharmaceutics, 281(1-2), 129-132 (2004-08-04)
Cell-based and acute and subchronic in vivo toxicity profiles of a dendrimer based on melamine reveal that this class of molecules warrants additional study as vehicles for drug delivery. In cell culture, a substantial decrease in viability was observed at
S A Tittlemier
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 27(2), 129-145 (2010-01-06)
In recent years, two adulteration incidents concerning the addition of melamine (MEL) and related compounds to dairy products and vegetable proteins have occurred in China. These episodes prompted numerous governmental and private laboratories to develop or implement methods for the
Yuejiao Wei et al.
Toxicology and industrial health, 28(7), 579-582 (2011-10-12)
In September 2008, in China, tens of thousands of children were hospitalized, several even died, as a result of infant-formula milk adulterated with a synthetic chemical compound, melamine, and in the next few months, this crisis became the focus of
Yongning Wu et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 56, 325-335 (2013-03-06)
This review summarizes the most recent scientific literature and regulations regarding analytical chemistry, toxicology, epidemiology, exposure, and risk assessment of melamine in infant formula. For analyses, enzyme-linked immunosorbent assay, high-performance liquid chromatography, capillary electrophoresis, gas chromatography coupled with mass spectrometry
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