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G7294

Sigma-Aldrich

Guanidine hydrochloride solution

8 M, pH 8.5, buffered aqueous solution

Synonym(s):

Aminoformamidine hydrochloride, Aminomethanamidine hydrochloride, GuHCl, Guanidine HCl, Guanidinium chloride, Guanidium chloride

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About This Item

UNSPSC Code:
12352209
NACRES:
NA.25

form

buffered aqueous solution

concentration

8 M

pH

8.5

application(s)

diagnostic assay manufacturing

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Urea and guanidine hydrochloride denaturation of ribonuclease, lysozyme, alpha-chymotrypsin, and beta-lactoglobulin.
R F Greene et al.
The Journal of biological chemistry, 249(17), 5388-5393 (1974-09-10)
The preparation of guanidine hydrochloride.
Nozaki, Yasuhiko
Methods in Enzymology, 26, 43-50 (1972)
Extended conformations of polypeptides and proteins in urea and guanidine hydrochloride.
Tiffany, M. Lois, and Samuel Krimm
Biopolymers, 12, 575-587 (1973)
Xin Fang et al.
Molecular medicine reports, 23(3) (2021-01-27)
In diabetic animal models, high plasma/tissue levels of methylglyoxal (MG) are implicated in atherosclerosis. N‑acetylcysteine (NAC) is a cysteine prodrug that replenishes intracellular glutathione (GSH) levels, which can increase the elimination of MG in diabetes mellitus (DM). The present study
Davide Gambarotto et al.
Nature methods, 16(1), 71-74 (2018-12-19)
Determining the structure and composition of macromolecular assemblies is a major challenge in biology. Here we describe ultrastructure expansion microscopy (U-ExM), an extension of expansion microscopy that allows the visualization of preserved ultrastructures by optical microscopy. This method allows for
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