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F1506

Sigma-Aldrich

Sodium fumarate dibasic

≥99%

Synonym(s):

Disodium fumarate, Fumaric acid disodium salt

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About This Item

Linear Formula:
NaOOCCH=CHCOONa
CAS Number:
17013-01-3
Molecular Weight:
160.04
Beilstein:
4301302
EC Number:
241-087-7
MDL number:
MFCD00064567
UNSPSC Code:
12352100
PubChem Substance ID:
24894772
NACRES:
NA.22

Assay

≥99%

SMILES string

[Na+].[Na+].[O-]C(=O)\C=C\C([O-])=O

InChI

1S/C4H4O4.2Na/c5-3(6)1-2-4(7)8;;/h1-2H,(H,5,6)(H,7,8);;/q;2*+1/p-2/b2-1+;;

InChI key

MSJMDZAOKORVFC-SEPHDYHBSA-L

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Application

  • Enhancement of drug absorption: Sodium fumarate dibasic is utilized to improve the dissolution behavior and oral absorption of drugs with pH-dependent solubility, enhancing bioavailability and therapeutic efficacy in pharmaceutical applications (Salehi et al., 2021).
  • Development of novel drug carriers: The compound is used in the synthesis and characterization of novel injectable drug carriers, aiming to enhance the delivery and efficacy of therapeutic agents in medical treatment strategies (Guo et al., 2005).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Miaomiao Jiang et al.
Scientific reports, 7(1), 8739-8739 (2017-08-20)
Metabonomics/metabolomics is a rapid technology for comprehensive profiling of small molecule metabolites in cells, tissues, or whole organisms, the application of which has led to understanding pathophysiologic mechanisms of cardiometabolic diseases, defining predictive biomarkers for those diseases, and also assessing
Wei Jin et al.
Current microbiology, 74(11), 1337-1342 (2017-08-02)
The effect of disodium fumarate (DF) on the ruminal fermentation profiles, the accumulation of lipopolysaccharide (LPS) and bioamines, and the composition of the ruminal bacterial community was investigated by in vitro rumen fermentation. The addition of DF increased the total
Xueying Liu et al.
Molecules (Basel, Switzerland), 24(12) (2019-06-21)
The major objective of this study was to investigate the anti-chronic nonbacterial prostatitis (CNP) mechanism of T. patula by metabolomics and network pharmacology. The study demonstrated that the flavonoids and polysaccharides of T. patula could alleviate prostatitis by improving the
Chandresh Thakker et al.
Biotechnology journal, 11(1), 80-90 (2015-08-19)
Various methods have been developed for gene disruption in bacteria; however, extra in vitro manipulation steps or the residual presence of a scar in the host chromosome limits the use of such methods. By utilizing the unique properties of ISHp608
Stanislaw J Gabryszewski et al.
American journal of respiratory cell and molecular biology, 61(2), 185-197 (2019-02-12)
Methicillin-resistant Staphylococcus aureus (MRSA) is a versatile human pathogen that is associated with diverse types of infections ranging from benign colonization to sepsis. We postulated that MRSA must undergo specific genotypic and phenotypic changes to cause chronic pulmonary disease. We
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