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form
lyophilized powder
extent of labeling
≥20 μmol per mL
technique(s)
affinity chromatography: suitable
matrix
cross-linked 4% beaded agarose
matrix active group
epoxy
matrix attachment
through epoxy to hydroxyl
matrix spacer
12 atoms
swelling
1 g swells to ~3 mL
suitability
suitable for chromatography
storage temp.
−20°C
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General description
Epoxy-activated-Agarose is a resin. Ligands can be covalently linked to agarose via the interaction of the nucleophilic groups of the ligand with the epoxy group.
when ligands are coupled to free epoxy groups. Linkage is a stable, uncharged ether.
Application
Epoxy-activated-Agarose is a lyophilized powder, stabilized with lactose, which is used in affinity chromatography, protein chromatography and activated/functionalized matrices. Epoxy-activated agarose has been used in studies informing anti-proliferative activity on human-derived cancer cells as well as cancer prevention.
Other Notes
Ligand: 1,4-bis(2:3-Epoxypropoxy)butane
Attachment: one epoxy group
Spacer: provides a 12-atom spacer when ligands are coupled to free epoxy groups. Linkage is a stable, uncharged ether.
Attachment: one epoxy group
Spacer: provides a 12-atom spacer when ligands are coupled to free epoxy groups. Linkage is a stable, uncharged ether.
Physical form
Lyophilized powder stabilized with lactose
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Donald Voet and Judith G. Voet
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