D9321

D-dimer, Human

from human plasma, buffered aqueous solution

• Synonym(s): Fibrin degradation fragment, Fragment D-dimer
• UNSPSC Code: 12352204
• NACRES: NA.61

Properties

• biological source: human plasma
• form: buffered aqueous solution
• mol wt: M_w ~200 kDa
• shipped in: wet ice
• storage temp.: −20°C

Description

General description

The human D-dimer(s) protein is an indicator of a thrombosis event. This protein is the degradation fragment of fibrin mesh that has been stabilized by Factor XIII. This factor crosslinks the E-element to two D-elements. As a result, this crosslink is the final step in the generation of a thrombus.

Application

The human D-dimer protein is a blood test performed in the medical laboratory to diagnose thrombosis. While a negative human D-dimer result rules out thrombosis, a positive test result can indicate thrombosis or other underlying potential health problems. The presence of D-dimer can idicate the existance of a deep venous thrombosis (DVT) or pulomonary embolism (PE).

Physical form

The human D-dimer protein provided in liquid form constisting of 0.05 M sodium phosphate, pH 7.5, 0.15 M sodium chloride and 0.09% sodium azide.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable