Skip to Content
Merck
All Photos(1)

Key Documents

C4361

Sigma-Aldrich

Bovine Collagen Type I

from bovine skin, liquid, 1 mg/mL, FITC Conjugated, used for gel analysis, cell seeding, and collagenase assays

Synonym(s):

Collagen from bovine skin

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

CAS Number:
308064-12-2
MDL number:
MFCD02264428
UNSPSC Code:
12352202
NACRES:
NA.32

product name

Collagen Type I−FITC Conjugate from bovine skin, ~1 mg/mL, solution

biological source

bovine skin

Quality Level

200

form

solution

concentration

~1 mg/mL

UniProt accession no.

P02453
P02465
P03956
P81563
Q9EPL5

shipped in

wet ice

storage temp.

−20°C

Gene Information

cow ... COL1A1(282187) , COL1A2(282188)
human ... MMP1 (includes EG:4312)
mouse ... MMP1 (includes EG:4312)
rat ... MMP1 (includes EG:4312)

General description

Type I collagen is the major collagen of tendon and bone, but it is widely distributed in other tissues, such as skin, cornea, tooth dentin, heart valve, lung, liver, fascia and scar tissue.

Application

Collagen Type I-FITC Conjugate from bovine skin has been used in collagen I gel deformation analysis. It has also been used to coat silicone elastic membranes for seeding cells for various experimental studies. It can also be used as a substrate for assaying mammalian collagenase activity in cell culture.

Biochem/physiol Actions

Collagen type I offers mechanical stability, strength and toughness to a range of tissues from tendons and ligaments, to skin, cornea, bone and dentin.

Physical form

Supplied in 0.01 M acetic acid.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Rachel M Brunetti et al.
The Journal of cell biology, 221(2) (2021-12-30)
To control their movement, cells need to coordinate actin assembly with the geometric features of their substrate. Here, we uncover a role for the actin regulator WASP in the 3D migration of neutrophils. We show that WASP responds to substrate
ROCK-and myosin-dependent matrix deformation enables protease-independent tumor-cell invasion in vivo
Wyckoff JB, et al.
Current Biology, 16(15), 1515-1523 (2006)
Collagen: structure and mechanics, an introduction
Collagen, 1-13 (2008)
Ayodele Olaolu Oladejo et al.
Journal of inflammation research, 15, 807-825 (2022-02-18)
Endometritis is a female reproductive disease that affects the cattle industries development and microRNAs (miRNAs) play a pivotal role and critical regulators of the innate immune response in varieties of diseases. The present study intends to investigate the regulatory role
F Nelson et al.
The Journal of clinical investigation, 102(12), 2115-2125 (1998-12-17)
There is evidence to suggest that the synthesis of type II collagen is increased in osteoarthritis (OA). Using an immunoassay, we show that the content of the C-propeptide of type II procollagen (CPII), released extracellularly from the newly synthesized molecule
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service