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Key Documents

76437

Sigma-Aldrich

Pentaethylene glycol monododecyl ether

BioXtra, ≥98.0% (GC)

Synonym(s):

C12E5, Dodecyl pentaethylene glycol ether, Dodecylpentaglycol, Polyoxyethylene (5) lauryl ether

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About This Item

Linear Formula:
CH3(CH2)11(OCH2CH2)5OH
CAS Number:
Molecular Weight:
406.60
Beilstein:
1797921
EC Number:
MDL number:
UNSPSC Code:
12161900
PubChem Substance ID:
NACRES:
NA.25

description

non-ionic

Quality Level

product line

BioXtra

Assay

≥98.0% (GC)

form

semisolid

mol wt

406.60 g/mol

technique(s)

drug transporter assay: suitable

density

0.963 g/mL at 20 °C (lit.)

cation traces

Ca: ≤50 mg/kg
Cd: ≤50 mg/kg
Co: ≤50 mg/kg
Cr: ≤50 mg/kg
Cu: ≤50 mg/kg
Fe: ≤50 mg/kg
K: ≤50 mg/kg
Mg: ≤50 mg/kg
Mn: ≤50 mg/kg
Na: ≤50 mg/kg
Ni: ≤50 mg/kg
Pb: ≤50 mg/kg
Zn: ≤50 mg/kg

SMILES string

CCCCCCCCCCCCOCCOCCOCCOCCOCCO

InChI

1S/C22H46O6/c1-2-3-4-5-6-7-8-9-10-11-13-24-15-17-26-19-21-28-22-20-27-18-16-25-14-12-23/h23H,2-22H2,1H3

InChI key

LAPRIVJANDLWOK-UHFFFAOYSA-N

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Application

<ul>
<li><strong>Coadsorption of a Monoclonal Antibody and Nonionic Surfactant at the SiO(2)/Water Interface:</strong> This study demonstrates the coadsorption properties of Pentaethylene glycol monododecyl ether with monoclonal antibodies, offering significant implications for biopharmaceutical formulations to improve drug stability and delivery (Lu et al., 2018).</li>
<li><strong>Water-Resistant Surface Modification of Hydrophobic Polymers with Water-Soluble Surfactant Additives:</strong> This research showcases the effectiveness of Pentaethylene glycol monododecyl ether in modifying hydrophobic polymer surfaces to make them water-resistant, pointing to its utility in various industrial and coating applications (Thompson et al., 2021).</li>
<li><strong>Synergistic Role of Temperature and Salinity in Aggregation of Nonionic Surfactant-Coated Silica Nanoparticles:</strong> Highlights the use of Pentaethylene glycol monododecyl ether in nanoparticle stabilization, particularly under varying thermal and saline conditions, beneficial for tailored drug delivery systems and environmental applications (Bharti et al., 2023).</li>
</ul>

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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K Selber et al.
Bioseparation, 10(4-5), 229-236 (2002-09-18)
The parameters important for an optimisation of cloud point extraction in technical scale were investigated using a genetically engineered fusion protein derived from endoglucanase I expressed in Trichoderma reesei and the nonionic polyoxyethylene Agrimul NRE 1205. The key parameters are
Venkatraman Ramanujam et al.
Frontiers in chemistry, 7, 889-889 (2020-02-11)
Disulfide bridges in proteins are formed by the oxidation of pairs of cysteine residues. These cross-links play a critical role in stabilizing the 3D-structure of small disulfide rich polypeptides such as hormones and venom toxins. The arrangement of the multiple
S Bulut et al.
The European physical journal. E, Soft matter, 27(3), 261-273 (2008-10-31)
We present a comprehensive study of the concentration-induced growth of nonionic wormlike micelles in dilute solutions, below the overlap concentration, where we combine static and dynamic light scattering and NMR self-diffusion. The data are analyzed in detail in terms of
U Sivars et al.
Journal of chromatography. B, Biomedical applications, 680(1-2), 43-53 (1996-05-17)
The study includes partitioning of proteins in aqueous two-phase systems consisting of the polymer dextran and the non-ionic surfactant C12E5 (pentaethylene glycol mono-n-dodecyl ether). In this system a micelle-enriched phase is in equilibrium with a polymer-enriched phase. Charges can be
Tiago Mendes Ferreira et al.
Physical chemistry chemical physics : PCCP, 10(39), 6033-6038 (2008-10-01)
A lyotropic nonionic lamellar system composed of pentaethyleneglycol mono n-dodecyl ether and D(2)O was studied using natural abundance (13)C NMR under magic-angle spinning. Applying a two-dimensional recoupling method proposed by Dvinskikh (R-PDLF), (1)H-(13)C dipolar couplings were estimated over a range

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