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42385

Sigma-Aldrich

Kollicoat® MAE 30 DP

46.0-50.6% methacrylic acid basis (calc. on solids content)

Synonym(s):

Methacrylic acid copolymer dispersion, Methacrylic acid-ethyl acrylate copolymer (1:1) dispersion 30 %

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About This Item

CAS Number:
25212-88-8
UNSPSC Code:
41116107
NACRES:
NA.25

concentration

46.0-50.6% (methacrylic acid, calc. on solids content)

impurities

≤1 ppm arsenic (verified on random samples only)
≤1.00% coagulum content /particulate matter
≤10 ppm heavy metals (verified on random samples only)

ign. residue

≤0.1%

evapn. residue (140 °C, 30 min.)

28.5-31.5%

loss

68.5-71.5% loss on drying, 140°C, 30 min.

pH

2.1-3.0

viscosity

≤15 mPa.s(20 °C) (apparent viscosity)
3-15(20 °C) (mm2/s)

density

1.062-1.072

InChI

1S/C5H8O2.C4H6O2/c1-3-5(6)7-4-2;1-3(2)4(5)6/h3H,1,4H2,2H3;1H2,2H3,(H,5,6)

InChI key

GDCRSXZBSIRSFR-UHFFFAOYSA-N

Application

Kollicoat polymers can be employed as film coatings (intelligent surfaces) with controlled-release agents, for instant-release or sustained-release applications. Kollicoat polymers can be used with all standard coating equipment and are cost-effective, delivering maximum quality in terms of function, stability, and appearance. This research grade product is intended for use in R&D and development only.

Analysis Note

appearance of a film : clear

Legal Information

Kollicoat is a registered trademark of BASF SE

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H332,H413

Precautionary Statements

P261

Hazard Classifications

Acute Tox. 4 Inhalation - Aquatic Chronic 4

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A Dashevsky et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 58(1), 45-49 (2004-06-23)
The objective of this study was to obtain pH-independent release profiles from coated pellets containing drugs with pH-dependent solubility. pH-independent release of the basic model drug verapamil HCl was achieved by coating with a combination of the neutral polymer dispersions
C Guthmann et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 69(2), 667-674 (2008-01-30)
The drug substance SAG/ZK has a short biological half-life and because of its weakly basic nature a strong pH-dependent solubility was observed. The aim of this study was to develop a controlled release (cr) multiple unit pellet formulation for SAG/ZK
Comparative studies with Kollicoat MAE 30 D and Kollicoat MAE 30 DP in aqueous spray dispersions and enteric coatings on highly swellable caffeine cores.
Dangel C, Schepky G, Reich HB, Kolter K.
Drug Devel. Ind. Pharm., 26, 415-421 (2000)
H Kranz et al.
International journal of pharmaceutics, 380(1-2), 112-119 (2009-07-28)
The major aim of this study was to identify an efficient tool to adjust drug release patterns from aqueous and organic ethylcellulose (a gastrointestinal insoluble polymer) coated pellets and to evaluate the long term stability of the film coatings. Drug

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