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53541

Supelco

Tulobuterol hydrochloride

VETRANAL®, analytical standard

Synonym(s):

2-tert-Butylamino-1-(2-chlorophenyl)ethanol hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C12H18ClNO · HCl
CAS Number:
56776-01-3
Molecular Weight:
264.19
MDL number:
MFCD00214398
UNSPSC Code:
41116107
PubChem Substance ID:
329757956
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

Assay

≥98.0% (HPLC)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable
solid phase extraction (SPE): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

2-8°C

SMILES string

Cl.CC(C)(C)NCC(O)c1ccccc1Cl

InChI

1S/C12H18ClNO.ClH/c1-12(2,3)14-8-11(15)9-6-4-5-7-10(9)13;/h4-7,11,14-15H,8H2,1-3H3;1H

InChI key

RSLNRVYIRDVHLY-UHFFFAOYSA-N

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General description

Standard for Supelco MIP SPE cartridges. For more information request Supelco Literature T407075, T706019, T706030, T706020
Tulobuterol hydrochloride is a sympathomimetic amine, possessing bronchodilator activity.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Tulobuterol hydrochloride may be used as a reference standard in determining the concentration of tulobuterol hydrochloride present in bovine liver homogenates and urine samples using gas chromatography coupled with tandem mass spectrometry (GC-MS-MS).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK9925
BCCH6222
BCCD9390
BCCC1945
BCBX5290

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Shuwa Minami et al.
Internal medicine (Tokyo, Japan), 47(6), 503-509 (2008-03-18)
There is insufficient evidence for the efficacy of a transdermal tulobuterol patch (TP), although combination therapy with bronchodilators is recommended for chronic obstructive pulmonary disease (COPD). A randomized, controlled crossover study was conducted to evaluate the clinical efficacy and safety
Ki-Seok Kim et al.
Colloids and surfaces. B, Biointerfaces, 92, 240-245 (2011-12-30)
Porous poly(ε-caprolactone) (PCL)/Eudragit RS 100 (ERS-100) microcapsules containing tulobuterol-adsorbed silica nanotubes (S-NTs) were prepared using a solvent evaporation method. The release behaviors of the PCL/ERS-100 microcapsules were investigated as a function of S-NT content. The PCL/ERS-100 microcapsules showed a stable
Determination of tulobuterol in human plasma by capillary gas chromatography
Wood G S and Chasseaud F L.
Journal of Chromatography. B, Biomedical Sciences and Applications, 416, 154-159 (1987)
Masakazu Ichinose et al.
Respiratory medicine, 104(2), 267-274 (2009-10-31)
The current mainstream treatment for COPD is bronchodilators alone or in combination. The effects of a beta(2)-agonist, tulobuterol, administered transdermally, have been reported to last for 24h. However, there are no reports on the efficacy of tulobuterol combined with an
Determination of β2-receptor agonists in bovine urine and liver by gas chromatography?tandem mass spectrometry
Leyssens L, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 564(2), 515-527 (1991)
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