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Clopidol

VETRANAL®, analytical standard

Synonym(s):

3,5-Dichloro-2,6-dimethyl-4-pyridinol

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About This Item

Empirical Formula (Hill Notation):
C7H7Cl2NO
CAS Number:
Molecular Weight:
192.04
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

Cc1nc(C)c(Cl)c(O)c1Cl

InChI

1S/C7H7Cl2NO/c1-3-5(8)7(11)6(9)4(2)10-3/h1-2H3,(H,10,11)

InChI key

ZDPIZLCVJAAHHR-UHFFFAOYSA-N

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General description

Clopidol belongs to the anticoccidial class of drugs.

Application

Clopidol may be used as a reference standard for the determination of clopidol in:
  • Bovine muscle, animal tissues and eggs by hydrophilic interaction liquid chromatography-tandem mass spectrometry (HILIC-MS/MS).
  • Environmental water samples by on-line solid phase extraction (SPE) and ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS).
  • Chicken processed foods and muscles by solid-supported liquid extraction (SLE) clean-up and LC-MS/MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Determination of 18 veterinary antibiotics in environmental water using high-performance liquid chromatography-q-orbitrap combined with on-line solid-phase extraction.
Kim C, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 1084(5-6), 158-165 (2018)
Analysis of 76 veterinary pharmaceuticals from 13 classes including aminoglycosides in bovine muscle by hydrophilic interaction liquid chromatography-tandem mass spectrometry.
Dasenaki ME, et al.
Journal of Chromatography A, 1452(5-6), 67-80 (2016)
G Dusi et al.
Journal of chromatography. A, 882(1-2), 79-84 (2000-07-15)
A rapid and very effective analytical procedure for the simultaneous liquid chromatographic determination of two coccidiostats, clopidol (CLOP) and nicarbazin (NICA), in poultry feeds was developed and tested. The ground feed samples were extracted using aqueous dimethylformamide after moistening with
Miry Blich et al.
The Journal of invasive cardiology, 22(10), 461-464 (2010-10-15)
Traditionally, stent thrombosis (STH) has been regarded as a complication of percutaneous coronary interventions during the first 30 post-procedural days. However, delayed endothelialization associated with the implantation of drug-eluting stents (DES) may extend the risk of thrombosis beyond 30 days.
R Malisch
Zeitschrift fur Lebensmittel-Untersuchung und -Forschung, 184(6), 467-477 (1987-06-01)
Chloramphenicol and meticlorpindol may be determined by HPLC with UV-detection with a limit of 0.02-0.03 mg/kg. Residues of 0.001 mg/kg Chloramphenicol are determined by Capillary-GC with an ECD after an additional clean up step using chromatography on a miniaturized silica

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